Abstract
The aim of this paper is to study urinary5-hydroxyindoleacetic acid (5-HIAA) in gastric cancer patients with a biochemical method and compare this metabolite with normal control and individuals with chronic gastritis. The subjects were 48 histologically proven gastric adenocarcinoma patients. They were 10 women and 38 men with mean age of 63.73 years. For determination of urinary excretion of 5-HIAA, a biochemical method was applied. According to kit protocol, the patients' fresh urine was added to the reagent material, and the color of the sediment that was the result of interaction between 5-HIAA and the mercury salt was compared with the standard colorimetric plate of the kit. The same method was also performed for a group of 47 patients with chronic gastritis and also a group of 50 normal individuals (age and sex matched). Urinary 5-HIAA was significantly higher in gastric cancer patients compared to individuals with chronic gastritis and normal controls (P value <0.001), but no association was detected in urinary 5-HIAA based on age, sex, or site of tumor and tumor grade in gastric cancer patients group. Also, no significant difference was noted in 5-HIAA excretion between chronic gastritis and normal control groups. Urina...Continue Reading
References
Dec 22, 1986·The American Journal of Medicine·J M Feldman, T M O'Dorisio
Dec 2, 1993·International Journal of Cancer. Journal International Du Cancer·P PisaniJ Ferlay
Jul 18, 2003·European Journal of Gastroenterology & Hepatology·H VäänänenP Sipponen
Apr 8, 2004·World Journal of Gastroenterology : WJG·Nevin IlhanMehmet Kucuksu
Nov 17, 2006·Cancer Research·Carsten DenkertOliver Fiehn
Mar 1, 2008·The Lancet Oncology·Wai K LeungUNKNOWN Asia Pacific Working Group on Gastric Cancer
May 30, 2008·Journal of Proteome Research·Daniel MonleónBernardo Celda
Nov 14, 2008·NMR in Biomedicine·Daniel MonleónBernardo Celda
Nov 15, 2008·Molecular & Cellular Proteomics : MCP·Kyoungmi KimRobert H Weiss
Jan 20, 2009·Journal of Pharmaceutical and Biomedical Analysis·Chao TanChengyun Xia
May 22, 2009·Cancer Research·Akiyoshi HirayamaTomoyoshi Soga
Sep 1, 2009·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Hao WuXizhong Shen
Sep 29, 2009·Bioinformatics·Hojung NamDoheon Lee
Dec 17, 2009·Analytical and Bioanalytical Chemistry·Hao WuXizhong Shen
Feb 8, 2011·CA: a Cancer Journal for Clinicians·Ahmedin JemalDavid Forman
Feb 26, 2011·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayDonald Maxwell Parkin
Mar 11, 2011·World Journal of Gastroenterology : WJG·Jun-Duo HuJin-Lian Chen
Jun 28, 2011·Gastroenterology·Susumu AikouSachiyo Nomura
Nov 30, 2011·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·Hu SongBi-Yan Lu
Jan 22, 2013·CA: a Cancer Journal for Clinicians·Rebecca SiegelAhmedin Jemal
Citations
Oct 21, 2016·Journal of Neuro-oncology·Noble Kumar TalariPrakash Babu Phanithi
Aug 11, 2015·Diseases·Mukesh Verma, Hirendra Nath Banerjee
Jan 28, 2021·Cancers·Beatriz JiménezAndrea Frilling
Dec 10, 2020·Frontiers in Zoology·Dandan JiangHairui Wang
Aug 25, 2021·Biochimica Et Biophysica Acta. Reviews on Cancer·Di YeFeng Bi
Oct 1, 2021·Frontiers in Oncology·Xin ChenHong-Gang Zheng