Determining between chyle leak and anastomotic leak after esophageal reconstruction: the utility of methylene blue dye

The Laryngoscope
Shivam KapilaSian Fairbank

Abstract

Two common complications of esophagectomy and immediate reconstruction comprise thoracic duct injury leading to chyle leak and anastomotic leakage. These can delay optimized nutrition, speech, and swallowing rehabilitation, and thus are important to identify and treat accordingly. When either chyle leak or anastomotic leak are clinically suspected, differentiation between the two can be very difficult clinically. As both complications may result in an increase in drain output once oral intake has occurred, an effective, quick, and accurate tool is required to determine whether this increase in drain output is related to an anastomotic leak or with a increase activity in chyle production. Retrospective descriptive study. Description of the use of oral methylene blue dye as a safe, simple, and quick clinical bedside test. When ingested orally, an anastomotic leak will lead to blue dye staining the neck drain output immediately (within seconds to minutes). A chyle leak may also result in blue staining of the drain output; however, this is not an immediate phenomenon, and rather, based on the bioavailability of methylene blue this would take a minimum of 1 hour, and more likely up to 4 hours, as the dye is absorbed into mesenteric ...Continue Reading

References

Apr 1, 1990·Journal of Surgical Oncology·S SarkarM S Mehta
Jun 15, 2007·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·R F D van la ParraF A Pameijer
Jun 21, 2007·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Sukumaran K NairMartin P Hayward
Sep 24, 2008·European Journal of Clinical Pharmacology·Ingeborg Walter-SackGerd Mikus
Aug 26, 2009·Radiology·Marcus SeegerJochen Hampe

❮ Previous
Next ❯

Citations

Mar 2, 2013·Current Opinion in Otolaryngology & Head and Neck Surgery·Corrado C CampisiCorradino Campisi
Jan 5, 2018·Laryngoscope Investigative Otolaryngology·Kimberley L KiongN Gopalakrishna Iyer
May 17, 2017·Current Treatment Options in Gastroenterology·Milena Di LeoAlessandro Repici
Jan 4, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Bina TariqLaura W J Baijens
Feb 9, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·N FarkasS Thomson

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

Scandinavian Journal of Thoracic and Cardiovascular Surgery
G M Hambraeus, B S Walther
Journal of Veterinary Pharmacology and Therapeutics
G Ziv, J E Heavner
Biological Psychiatry
J P MoodyG J Naylor
The Annals of Thoracic Surgery
M J KrasnaJ F Biedlingmaier
© 2022 Meta ULC. All rights reserved