Detoxification of benzidine-based azo dye by E. gallinarum: time-course study

Ecotoxicology and Environmental Safety
Amit BafanaGajanan Kanade

Abstract

Direct black 38 (DB38) dye is a well-established toxic and carcinogenic compound. Present investigation reports isolation of an Enterococcus gallinarum strain capable of decolorizing and degrading it. Changes in toxicity and mutagenicity of DB38 and its metabolites were also determined using a battery of carefully selected tests (cytotoxicity, respiration inhibition test and Ames test). Toxicity assays were carried out on E. gallinarum itself as this also gave information about suitability of this strain for the dye decolorization operation. The strain was found to reduce both toxicity and mutagenicity of DB38 metabolites. Benzidine and 4-aminobiphenyl (4-ABP) were identified as the DB38 metabolites, responsible for its toxic and mutagenic properties, by HPLC-MS analysis. Further degradation of benzidine and 4-ABP was found to result in the decrease in toxicity and mutagenicity.

References

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Citations

Jan 13, 2012·Applied Biochemistry and Biotechnology·Marcos Erick Rodrigues da SilvaAndré Bezerra Dos Santos
Oct 30, 2016·Bioresource Technology·Jyoti TiwariAmit Bafana
Feb 11, 2015·Critical Reviews in Biotechnology·Shahid MahmoodDavid E Crowley
Nov 20, 2019·International Microbiology : the Official Journal of the Spanish Society for Microbiology·Mehvish AjazAbdul Rehman
Oct 13, 2021·Environmental Science and Pollution Research International·Jyotsna KaushalNavjeet Kaur

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