Abstract
Nocturia, a common symptom of overactive bladder syndrome, is associated with substantial adverse consequences and yet its pathophysiology has hardly been studied and the capacity to treat it remains limited. We established methods to study the physiology of overactive bladder associated nocturia and better understand this phenomenon. We recorded simultaneous, time aligned, nocturnal cystometrogram and polysomnogram data during a single night at a sleep laboratory in 9 patients with overactive bladder and detrusor overactivity on daytime cystometrogram, in 10 patients with insomnia and in 5 healthy controls. We safely recorded simultaneous polysomnography/nocturnal cystometrography data accurately during the sleep period. Nocturnal detrusor overactivity occurred significantly less often in patients with insomnia and controls than in patients with detrusor overactivity plus overactive bladder (p = 0.02) and only in the 10 minutes before nocturia events in the latter (0%, 0% and 67%, respectively, p = 0.002). Patients with detrusor overactivity plus overactive bladder were awake for a shorter period before nocturia events (p <0.001) and had a greater percent of nocturia associated awakenings. Patients with insomnia had more awake...Continue Reading
References
May 1, 1992·The Journal of Urology·E S van Waalwijk van DoornR A Janknegt
Aug 1, 1994·Psychiatry Research·G S BrussJ P Barber
Oct 17, 1998·Neurourology and Urodynamics·J P WeissM M Brooks
Aug 25, 1999·Current Opinion in Urology·J Sullivan, P Abrams
Sep 1, 1999·BJU International·R Asplund
Aug 23, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M A KisleyR Freedman
Feb 22, 2002·Neurourology and Urodynamics·Philip van KerrebroeckUNKNOWN Standardisation Sub-committee of the International Continence Society
Apr 12, 2002·Neurourology and Urodynamics·Werner SchäferUNKNOWN International Continence Society
Jun 18, 2003·Urology·Teh-Wei HuTimothy L Hunt
Jun 18, 2003·World Journal of Urology·W F StewartA J Wein
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Nov 25, 2003·BJU International·K S CoyneE Versi
Dec 10, 2003·Urology·Paul Abrams
Feb 20, 2004·The New England Journal of Medicine·Joseph G Ouslander
Mar 12, 2004·Urology·Masaki YoshidaAkito Inadome
Feb 14, 2006·Nature Clinical Practice. Urology·Karl-Erik Andersson
Oct 3, 2006·International Journal of Urology : Official Journal of the Japanese Urological Association·Noritoshi SekidoHideyuki Akaza
Oct 17, 2006·Sleep·Daniel J BuysseCharles M Morin
Oct 21, 2006·The Cochrane Database of Systematic Reviews·G NabiJ Hay-Smith
Aug 3, 2007·BJU International·Osamu YamaguchiUNKNOWN Japanese Solifenacin Study Group
Aug 29, 2007·Neurourology and Urodynamics·Samih Al-HayekPaul Abrams
Sep 8, 2007·BJU International·Dudley RobinsonUNKNOWN Tamsulosin Study Group
Apr 1, 2008·Journal of Psychiatric Research·Maurice M Ohayon
Aug 16, 2008·Current Urology Reports·Jeffrey P WeissJerry G Blaivas
Dec 18, 2008·Neurourology and Urodynamics·Ling-Hong TsengYet-Jane Ko
Citations
Aug 3, 2012·International Urogynecology Journal·Xavier A Preud'hommeAndrew D Krystal
Nov 1, 2011·Journal of the Chinese Medical Association : JCMA·Yu-Hua FanKuang-Kuo Chen
Apr 9, 2013·The Journal of Urology·Tomas L Griebling
Jun 16, 2012·Urology·Kaan BalGalip Akhan
Apr 18, 2015·Urology·Stephen D MarshallUNKNOWN International Consultations on Urological Diseases
Jul 28, 2016·Nature Reviews. Urology·Hasan DaniJeffrey P Weiss
Sep 30, 2016·The Journal of Urology·Shachi TyagiNeil M Resnick
Apr 2, 2017·Sleep·Andrew D Krystal, Xavier A Preud'homme
May 3, 2016·F1000Research·Arman A Kahokehr, Peter J Gilling
May 20, 2016·Investigative and Clinical Urology·Jin Wook KimKyung Do Kim
Oct 14, 2017·F1000Research·Noam D FineAlan J Wein
Mar 9, 2020·International Urogynecology Journal·Ismaiel Abu MahfouzHashim Hashim
Aug 10, 2011·Neurourology and Urodynamics·Sung Yong ChoSeung-June Oh