Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop

Journal of Biomedical Informatics
Kathleen M JagodnikAvi Ma'ayan

Abstract

The volume and diversity of data in biomedical research have been rapidly increasing in recent years. While such data hold significant promise for accelerating discovery, their use entails many challenges including: the need for adequate computational infrastructure, secure processes for data sharing and access, tools that allow researchers to find and integrate diverse datasets, and standardized methods of analysis. These are just some elements of a complex ecosystem that needs to be built to support the rapid accumulation of these data. The NIH Big Data to Knowledge (BD2K) initiative aims to facilitate digitally enabled biomedical research. Within the BD2K framework, the Commons initiative is intended to establish a virtual environment that will facilitate the use, interoperability, and discoverability of shared digital objects used for research. The BD2K Commons Framework Pilots Working Group (CFPWG) was established to clarify goals and work on pilot projects that address existing gaps toward realizing the vision of the BD2K Commons. This report reviews highlights from a two-day meeting involving the BD2K CFPWG to provide insights on trends and considerations in advancing Big Data science for biomedical research in the Unite...Continue Reading

Citations

Dec 1, 2017·Briefings in Bioinformatics·Jessica D TenenbaumLeon Rozenblit
Jun 20, 2018·Scientific Data·Vasileios StathiasStephan C Schürer
Nov 27, 2018·Oral Diseases·Shanika NanayakkaraHeiko Spallek
Feb 23, 2019·Journal of Neurotrauma·Bridget E HawkinsAdam R Ferguson
Dec 19, 2017·PloS One·Maria PanteliSimon Dixon
Oct 26, 2018·F1000Research·Vivek Navale, Matthew McAuliffe
Nov 2, 2019·Scientific Data·Maxime JanIoannis Xenarios
Jun 15, 2018·PLoS Computational Biology·Vivek Navale, Philip E Bourne
Mar 7, 2020·JCO Clinical Cancer Informatics·Fadila ZerkaPhilippe Lambin
Jun 26, 2021·Stem Cells and Cloning : Advances and Applications·Kirill Borziak, Joseph Finkelstein
Mar 18, 2019·Journal of Biomedical Informatics·Bei LiXiaoyun Lan

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