Developing a vaccine for Haemophilus influenzae serotype a: Proceedings of a workshop

Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada
Andrew D CoxConference contributors

Abstract

Since the late 1990s there has been an emergence of Haemophilus influenzae serotype a (Hia) infections, especially in Indigenous communities in the northern regions of Canada and Alaska associated with significant morbidity and approximately a 10% mortality. A Hia vaccine could potentially prevent this disease and save the health care system millions of dollars in both acute and long-term care. On March 23-24, 2016, the National Research Council (NRC), the Public Health Agency of Canada (PHAC) and the Canadian Institutes of Health Research (CIHR) co-organized a meeting on H. influenzae serotype a (Hia) to examine the current state of disease epidemiology and a potential vaccine solution path. The meeting included representatives from academia, federal and territorial public health units, hospital laboratories, federal departments involved in Aboriginal health, advocacy organizations for Indigenous peoples and industry. Representatives from industry confirmed having the capacity and the interest to support preparation of clinical trial batches. Canadian regulatory authorities have expressed a willingness to help ensure appropriate measures are in place for licensure purposes. Furthermore, there is the capacity and interest in pe...Continue Reading

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Citations

Dec 6, 2018·Frontiers in Immunology·Manish Sadarangani
Jun 27, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marina Ulanova
May 18, 2018·Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada·L BarretoRsw Tsang
Jun 27, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Heidi M SoetersMichael G Bruce
Mar 30, 2021·Russian Journal of Bioorganic Chemistry·E A Khatuntseva, N E Nifantiev
Jun 3, 2021·Clinical Microbiology Reviews·M P E SlackM Ulanova

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