Development and characterization of the InVesalius Navigator software for navigated transcranial magnetic stimulation

Journal of Neuroscience Methods
Victor Hugo SouzaOswaldo Baffa

Abstract

Neuronavigation provides visual guidance of an instrument during procedures of neurological interventions, and has been shown to be a valuable tool for accurately positioning transcranial magnetic stimulation (TMS) coils relative to an individual's anatomy. Despite the importance of neuronavigation, its high cost, low portability, and low availability of magnetic resonance imaging facilities limit its insertion in research and clinical environments. We have developed and validated the InVesalius Navigator as the first free, open-source software for image-guided navigated TMS, compatible with multiple tracking devices. A point-based, co-registration algorithm and a guiding interface were designed for tracking any instrument (e.g. TMS coils) relative to an individual's anatomy. Localization, precision errors, and repeatability were measured for two tracking devices during navigation in a phantom and in a simulated TMS study. Errors were measured in two commercial navigated TMS systems for comparison. Localization error was about 1.5 mm, and repeatability was about 1 mm for translation and 1° for rotation angles, both within limits established in the literature. Existing TMS neuronavigation software programs are not compatible wit...Continue Reading

Citations

Aug 28, 2020·Frontiers in Neuroscience·Sergio Luiz NoviRickson C Mesquita

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