Development and evaluation of a double-check support system using artificial intelligence in endoscopic screening for gastric cancer.

Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Hirotaka OuraNaoya Kato


This study aimed to prevent missing gastric cancer and point out low-quality images by developing a double-check support system (DCSS) for esophagogastroduodenoscopy (EGD) still images using artificial intelligence. We extracted 12,977 still EGD images from 855 cases with cancer [821 with early gastric carcinoma (EGC) and 34 malignant lymphoma (ML)] and developed a lesion detection system using 10,994 images. The remaining images were used as a test dataset. Additional validation was performed using a new dataset containing 50 EGC and 1,200 non-GC images by comparing the interpretation of ten endoscopists (five trainees and five experts). Furthermore, we developed another system to detect low-quality images, which are not suitable for diagnosis, using 2198 images. In the validation of 1983 images from the 124 cancer cases, the DCSS diagnosed cancer with a sensitivity of 89.2%, positive predictive value (PPV) of 93.3%, and an accuracy of 83.3%. EGC was detected in 93.2% and ML in 92.5% of cases. Comparing with the endoscopists, sensitivity was significantly higher in the DCSS, and the average diagnostic time was significantly shorter using the DCSS than that by the trainees. The sensitivity, specificity, PPV, and accuracy in det...Continue Reading


Dec 15, 1986·International Journal of Cancer. Journal International Du Cancer·A OshimaI Fujimoto
Jan 3, 1995·International Journal of Cancer. Journal International Du Cancer·A FukaoA Takano
Feb 22, 2002·International Journal of Cancer. Journal International Du Cancer·René LambertHideaki Tsukuma
Apr 17, 2008·Scandinavian Journal of Gastroenterology·Masako OguraMasao Omata
Jul 9, 2008·Scandinavian Journal of Gastroenterology·Osamu HosokawaHiroyuki Aoyagi
Dec 17, 2010·World Journal of Gastrointestinal Oncology·Angelo ZulloSergio Morini
Feb 1, 2013·International Journal of Cancer. Journal International Du Cancer·Chisato HamashimaTakuji Kishimoto
Sep 3, 2013·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Satohiro Matsumoto, Yukio Yoshida
Apr 26, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Hiroshi SanoChisato Hamashima
Mar 6, 2015·World Journal of Gastroenterology : WJG·Chisato HamashimaSatoshi Tsukioka
Oct 4, 2015·Cancer Science·Chisato HamashimaYoneatsu Osaki
Dec 15, 2015·IEEE Transactions on Pattern Analysis and Machine Intelligence·Ross GirshickJitendra Malik
May 6, 2016·European Journal of Gastroenterology & Hepatology·Ana Rita Pimenta-MeloMário Dinis-Ribeiro
Oct 12, 2016·Cancer Science·Chisato Hamashima, Rei Goto
Jan 18, 2018·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Toshiaki HirasawaTomohiro Tada
Nov 19, 2018·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Mitsuaki IshiokaTomohiro Tada
Jul 10, 2019·BMC Gastroenterology·Rui GuoHui-Hong Zhai
Oct 18, 2019·Yeungnam University Journal of Medicine·Byung Sam Park, Si Hyung Lee
Dec 4, 2019·IEEE Transactions on Pattern Analysis and Machine Intelligence·Zhaowei Cai, Nuno Vasconcelos
Apr 14, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Yohei IkenoyamaTomohiro Tada
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