Development and evaluation of Classical and Pickering emulsions containing crude or fractionated extracts of Libidibia ferrea pods.

Drug Development and Industrial Pharmacy
Magda Rhayanny Assunção FerreiraLuiz Alberto Lira Soares

Abstract

Objective: The development of medicinal plants for clinical use represents an important direction in biomedical research, despite the technological difficulties.Significance: The aim of this study was to compare pharmaceutical characteristics and in vitro release of Classical and Pickering emulsions containing crude or fractionated extracts of Libidibia ferrea.Methods: After evaluating the extract's solubility in formulation, a dispersion of hydroxypropyl methylcellulose (HPMC) was prepared in water. For Pickering emulsions, the aqueous phase was HPMC and the oil phase was Miglyol® 812; for Classical emulsions, water with Tween® 20 and Miglyol® 812 with Span® 80 were used for aqueous and oil phases, respectively. Crude or fractionated extracts were added to the aqueous phase (5% w/v). Both phases were heated (40 °C); then, the oil phase was poured into the aqueous phase and homogenized using an Ultra-Turrax. Emulsions were characterized for 90 days by pH, polyphenol content, phytomarker content, macroscopic characteristics, droplet size, and zeta potential.Results: These formulations displayed satisfactory stability for 90 days when stored at 25 °C. Regarding the investigation of rheological properties, Pickering emulsions disp...Continue Reading

References

May 9, 2000·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·M B Schulz, R Daniels
Sep 9, 2010·AAPS PharmSciTech·Magda R A FerreiraLuiz A L Soares
Jul 4, 2012·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Dominique Jasmin Lunter, Rolf Daniels
Jun 15, 2013·International Journal of Cosmetic Science·O V ZillichM Kerscher
Oct 8, 2013·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Michael RottkeRolf Daniels
Feb 26, 2015·International Journal of Cosmetic Science·O V ZillichM Kerscher
Sep 15, 2015·Pharmaceutical Development and Technology·Audrey Alesandra Stinghen Garcia LonniJoão Carlos Palazzo de Mello
Apr 5, 2016·Journal of Colloid and Interface Science·Laudina J DuffusFotios Spyropoulos
Jul 5, 2016·International Journal of Molecular Sciences·Letícia StreckArnóbio Antônio da Silva-Júnior
Jun 7, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Andreza Conceição Véras de Aguiar GuerraRaimundo Fernandes de Araújo Júnior
Nov 23, 2017·Physical Chemistry Chemical Physics : PCCP·Wu LiGregory J O Martin
Sep 12, 2018·European Journal of Medicinal Chemistry·Giulia Martelli, Daria Giacomini
Jan 3, 2019·Carbohydrate Polymers·Xiang LiXiaofeng Sui
Mar 28, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Tamires Rocha FalcãoGerlane Coelho Bernardo Guerra
Jul 2, 2019·Acta Pharmaceutica : a Quarterly Journal of Croatian Pharmaceutical Society and Slovenian Pharmaceutical Society, Dealing with All Branches of Pharmacy and Allied Sciences·Renata RutckeviskiEryvaldo Socrates Tabosa Do Egito

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