Development and Function of the Drosophila Tracheal System

Genetics
Shigeo Hayashi, Takefumi Kondo

Abstract

The tracheal system of insects is a network of epithelial tubules that functions as a respiratory organ to supply oxygen to various target organs. Target-derived signaling inputs regulate stereotyped modes of cell specification, branching morphogenesis, and collective cell migration in the embryonic stage. In the postembryonic stages, the same set of signaling pathways controls highly plastic regulation of size increase and pattern elaboration during larval stages, and cell proliferation and reprograming during metamorphosis. Tracheal tube morphogenesis is also regulated by physicochemical interaction of the cell and apical extracellular matrix to regulate optimal geometry suitable for air flow. The trachea system senses both the external oxygen level and the metabolic activity of internal organs, and helps organismal adaptation to changes in environmental oxygen level. Cellular and molecular mechanisms underlying the high plasticity of tracheal development and physiology uncovered through research on Drosophila are discussed.

References

Jan 1, 1996·Genes & Development·D D Isaac, D J Andrew
Nov 11, 1998·Molecular Cell·S VincentM Leptin
Aug 15, 2002·Mechanisms of Development·Tomokazu OhshiroKaoru Saigo
Jun 5, 2003·The Journal of Cell Biology·Jennifer L Genova, Richard G Fehon
Dec 5, 2003·Mechanisms of Development·Jinghong LiWillis X Li
Dec 29, 2004·Current Biology : CB·Carlos RibeiroMarkus Affolter
Nov 17, 2005·Proceedings of the National Academy of Sciences of the United States of America·W Patrick DevineMark A Krasnow
Dec 6, 2005·Developmental Cell·Clemens Cabernard, Markus Affolter

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Citations

Nov 6, 2018·Histochemistry and Cell Biology·Johannes C Schittny
Feb 26, 2019·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Kristy Red-Horse, Arndt F Siekmann
Aug 28, 2020·Wiley Interdisciplinary Reviews. Developmental Biology·Edel Alvarez-OchoaLouise Y Cheng
Jul 19, 2019·The Journal of Cell Biology·Kassiani SkouloudakiDimitrios K Papadopoulos
Feb 12, 2020·Proceedings of the National Academy of Sciences of the United States of America·Lisa Hanna, Aleksandar Popadić
Mar 3, 2021·Proceedings of the National Academy of Sciences of the United States of America·Seonghan JangYoshitomo Kikuchi
Mar 20, 2021·Proceedings of the National Academy of Sciences of the United States of America·Di ChenJules A Hoffmann
Feb 24, 2021·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Yuki TairaYuji Kageyama
Mar 30, 2021·Frontiers in Cell and Developmental Biology·Anjeli MaseKatja Brückner
Mar 8, 2020·Seminars in Cell & Developmental Biology·Quentin Laurichesse, Cedric Soler
May 28, 2021·Nature Cell Biology·Louis Gervais, Allison J Bardin
May 19, 2021·Developmental Biology·Delia RicoloSofia J Araújo
Jun 3, 2021·International Journal of Molecular Sciences·Yi WeiCheng Lu
Jul 10, 2021·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Natalia MorachoCristina Sánchez-Camacho
Aug 15, 2021·Nature Reviews. Cancer·David BilderJung Kim
Nov 30, 2021·Biology Open·Mariana Barrera-Velázquez, Luis Daniel Ríos-Barrera
Jun 2, 2021·Seminars in Cell & Developmental Biology·Yu-Chiun Wang
Jan 22, 2022·The Journal of Cell Biology·Luis Daniel Ríos-Barrera, Maria Leptin

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