PMID: 6987330Jan 1, 1980Paper

Development and improvement of a commercial uric acid enzymatic determination kit on a centrifugal fast analyzer

Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Für Klinische Chemie Und Klinische Biochemie
F ZoppiD Fenili

Abstract

The performance of a uric acid determination kit has been evaluated for five months, under routine conditions, in a General Hospital Biochemical Laboratory. An anomalous increment in fresh serum blanks was noted in the kit when first introduced. This interference, probably due to alcohol dehydrogenase contamination, was corrected by addition of 50 mmol/l (NH4)2SO4 to the reagent. Results obtained with this modified reagent correlate perfectly with those obtained with modified kits by Smith Kline Instruments (SKI), and with many other determination methods. Correlations are discussed and explanations for differences in statistical data are offered. Within run and between run precision data are presented. The kit fits perfectly with the needs of centrifugal fast analyzers and discrete micro analyzers, on account of its speed, reliability and precision.

References

Nov 1, 1973·American Journal of Clinical Pathology·L G Morin, J Prox
Feb 1, 1971·Clinica Chimica Acta; International Journal of Clinical Chemistry·N Kageyama
Jan 1, 1953·Scandinavian Journal of Clinical and Laboratory Investigation·E PRAETORIUS, H POULSEN

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