Development and Testing of an Integrated Score for Physical Behaviors

Medicine and Science in Sports and Exercise
Sarah K KeadleRaymond J Carroll

Abstract

Interest in a variety of physical behaviors (e.g., exercise, sitting time, sleep) in relation to health outcomes creates a need for new statistical approaches to analyze the joint effects of these distinct but inter-related physical behaviors. We developed and tested an integrated physical behavior score (PBS). National Institutes of Health-American Association of Retired Persons Diet and Health Study participants (N = 163,016) completed a questionnaire (2004-2006) asking about time spent in five exercise and nonexercise physical activities, two sedentary behaviors (television and nontelevision), and sleep. In half of the sample, we used shape-constrained additive regression to model the relationship between each behavior and survival. Maximum logit scores from each of the eight behavior-survival functions were summed to produce a PBS that was proportionally rescaled to range from 0 to 100. We examined predictive validity of the PBS in the other half-sample using Cox Proportional Hazards models after adjustment for covariates for all-cause and cause-specific mortality. In the testing sample, over an average of 6.6 yr of follow-up, 8732 deaths occurred. We found a strong graded decline in risk of all-cause mortality across quint...Continue Reading

References

Oct 1, 1994·International Journal of Epidemiology·A M WolfW C Willett
Jun 3, 2008·The International Journal of Behavioral Nutrition and Physical Activity·Anne E CustAdrian Bauman
Oct 29, 2008·Journal of the American Dietetic Association·Patricia M GuentherBryce B Reeve
Oct 29, 2008·Journal of the American Dietetic Association·Patricia M GuentherSusan M Krebs-Smith
Jun 16, 2011·JAMA : the Journal of the American Medical Association·Anders Grøntved, Frank B Hu
Jun 21, 2013·American Journal of Epidemiology·Rania A MekaryEric L Ding
Oct 25, 2013·Medicine and Science in Sports and Exercise·Peter T Katzmarzyk
Aug 13, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·S A PrinceR D Reid
Jan 30, 2015·Medicine and Science in Sports and Exercise·Charles E MatthewsYikyung Park
Aug 17, 2016·Circulation·Deborah Rohm YoungUNKNOWN Physical Activity Committee of the Council on Lifestyle and Cardiometabolic Health; Council on Clinical Cardiology; Council
Nov 3, 2016·The American Journal of Clinical Nutrition·Charles E MatthewsDavid Berrigan
Apr 20, 2017·Journal of Physical Activity & Health·Sarah Kozey KeadleFrank M Perna
Jun 9, 2017·American Journal of Epidemiology·Kara M WhitakerMark A Pereira
Sep 21, 2017·Medicine and Science in Sports and Exercise·Charles E MatthewsJoshua N Sampson
Nov 13, 2018·JAMA : the Journal of the American Medical Association·Katrina L PiercyRichard D Olson

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Citations

Jun 11, 2021·Journal of Cancer Survivorship : Research and Practice·Shirley M BluethmannFrank M Perna

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