Development and Validation of a Tool for the Prediction of Vancomycin-Resistant Enterococci Colonization Persistence-the PREVENT Score.

Microbiology Spectrum
Christian BoeingStefanie Kampmeier


Vancomycin-resistant enterococci (VRE) are nosocomial pathogens with increasing prevalence worldwide. Extensive hygiene measures have been established to prevent infection transmission in hospitals. Here, we developed a predictive score system (the predictive vancomycin-resistant enterococci [PREVENT] score) to identify the clearance or persistence in patients with a history of VRE carrier status at readmission. Over a cumulative 3-year period, patients with a positive VRE carrier status were included. The study population was recruited in two successive time periods and separated into training data for predictive score development and validation data for evaluation of the predictive power. The risk factors for persistent VRE colonization were analyzed in a univariable analysis before development of a logistic regression model based on the potential risk factors. The score points were determined proportionally to the beta coefficients of the logistic regression model. The data from 448 (79%) patients were used as the training data, and those from 119 (21%) as the validation data. Multivariable analysis revealed the following variables as independent risk factors: age of ≥60 years, hemato-oncological disease, cumulative antibiot...Continue Reading


Jan 11, 2001·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·R PatelR L Thompson
Oct 12, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L R BadenG M Eliopoulos
Jun 6, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Carlene A MutoUNKNOWN SHEA
Sep 27, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Caroline Eva Wella HerrThomas Friedrich Eikmann
Oct 9, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Evelina TacconelliErika M C D'Agata
Jul 14, 2010·The Journal of Hospital Infection·C AbadN Safdar
Jun 15, 2011·The Journal of Hospital Infection·H R DayD J Morgan
Feb 14, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Sorabh DharKeith S Kaye
Apr 18, 2017·Antimicrobial Resistance and Infection Control·Lena M BiehlMaria J G T Vehreschild
May 16, 2018·Antimicrobial Resistance and Infection Control·Cornelius RemschmidtTobias Siegfried Kramer
Jan 18, 2019·The Journal of Hospital Infection·S Mohd Sazlly LimS M Liew

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