Development and validation of an efficient ultrasound assisted extraction of phenolic compounds from flax (Linum usitatissimum L.) seeds

Ultrasonics Sonochemistry
Cyrielle CorbinChristophe Hano

Abstract

Flaxseed accumulates in its seedcoat a macromolecular complex composed of lignan (secoisolariciresinol diglucoside, SDG), flavonol (herbacetin diglucoside, HDG) and hydroxycinnamic acids (p-couramic, caffeic and ferulic acid glucosides). Their antioxidant and/or cancer chemopreventive properties support their interest in human health and therefore, the demand for their extraction. In the present study, ultrasound-assisted extraction (UAE) of flaxseed phenolic compounds was investigated. Scanning Electron Microscopy imaging and histochemical analysis revealed the deep alteration of the seedcoat ultrastructure and the release of the mucilage following ultrasound treatment. Therefore, this method was found to be very efficient for the reduction of mucilage entrapment of flaxseed phenolics. The optimal conditions for UAE phenolic compounds extraction from flaxseeds were found to be: water as solvent supplemented with 0.2N of sodium hydroxide for alkaline hydrolysis of the SDG-HMG complex, an extraction time of 60 min at a temperature of 25°C and an ultrasound frequency of 30 kHz. Under these optimized and validated conditions, highest yields of SDG, HDG and hydroxycinnamic acid glucosides were detected in comparison to other publis...Continue Reading

References

Jan 1, 1995·Proceedings of the Society for Experimental Biology and Medicine·W R ObermeyerS W Page
Nov 18, 2000·Analytical Biochemistry·J LigginsS A Bingham
Nov 23, 2000·Journal of Agricultural and Food Chemistry·P JohnssonP Aman
Oct 3, 2003·Journal of Chromatography. a·Mauricio A RostagnoCarmelo G Barroso
Jul 12, 2007·Phytochemical Analysis : PCA·Vickram BeejmohunFrançois Mesnard
Mar 24, 2009·Journal of Applied Microbiology·K StruijsH Gruppen
Oct 29, 2010·Ultrasonics Sonochemistry·En-Qin XiaHua-Bin Li
Jul 19, 2011·Plant Foods for Human Nutrition·Agnieszka KosińskaRyszard Amarowicz
Feb 23, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ali KhoddamiThomas H Roberts
Mar 13, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ophélie FliniauxChristophe Hano

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Citations

Jul 29, 2015·Nutrition Journal·Muhammad ImranShahzad Hussain
Oct 25, 2016·Ultrasonics Sonochemistry·I Ganesh MoorthyB Priya
May 29, 2019·Artificial Cells, Nanomedicine, and Biotechnology·Bilal Haider AbbasiChristophe Hano
Apr 5, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Maša Islamčević RazboršekMitja Kolar
Sep 22, 2020·Critical Reviews in Analytical Chemistry·Sing Chuong ChuoAbdullah Alarifi
May 27, 2021·Environmental Science and Pollution Research International·Manhattan LebrunSylvain Bourgerie
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rocco GiordanoAllan Stensballe
Jul 20, 2020·Food Chemistry·Renata Masur Carneiro da CunhaPatrícia Moreira Azoubel
Oct 27, 2021·Journal of Natural Products·Yajia GuoMartin J T Reaney

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