Development and validation of the Medication Regimen Simplification Guide for Residential Aged CarE (MRS GRACE)

Clinical Interventions in Aging
Esa Y H ChenJ Simon Bell

Abstract

Residents of aged care facilities use increasingly complex medication regimens. Reducing unnecessary medication regimen complexity (eg, by consolidating the number of administration times or using alternative formulations) may benefit residents and staff. To develop and validate an implicit tool to facilitate medication regimen simplification in aged care facilities. A purposively selected multidisciplinary expert panel used modified nominal group technique to identify and prioritize factors important in determining whether a medication regimen can be simplified. The five prioritized factors were formulated as questions, pilot-tested using non-identifiable medication charts and refined by panel members. The final tool was validated by two clinical pharmacists who independently applied the tool to a random sample of 50 residents of aged care facilities to identify opportunities for medication regimen simplification. Inter-rater agreement was calculated using Cohen's kappa. The Medication Regimen Simplification Guide for Residential Aged CarE (MRS GRACE) was developed as an implicit tool comprising of five questions about 1) the resident; 2) regulatory and safety requirements; 3) drug interactions; 4) formulation; and 5) facility...Continue Reading

Citations

Jan 31, 2019·Journal of the American Geriatrics Society·Terri R Fried, Marcia C Mecca
Dec 15, 2020·Journal of Clinical Lipidology·Leonie PictonJenni Ilomäki
Jan 20, 2021·PloS One·Confidence Alorse AtakroIsaac Kwadwo Ansong
May 1, 2021·International Journal of Environmental Research and Public Health·Jungwon ChoEuni Lee
Jun 27, 2021·Journal of Pharmacy Practice and Research : Official Journal of the Society of Hospital Pharmacists of Australia·Ian A ScottSarah N Hilmer

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Methods Mentioned

BETA
pharmacotherapy

Software Mentioned

MRS GRACE
SAS
Excel
SImplification
NGT

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