Development of a claims-based algorithm to identify colorectal cancer recurrence

Annals of Epidemiology
A D DeshpandeAllese Mayer

Abstract

To examine the validity of claims data to identify colorectal cancer (CRC) recurrence and determine the extent to which misclassification of recurrence status affects estimates of its association with overall survival in a population-based administrative database. We calculated the accuracy of claims data relative to medical records from one large tertiary hospital to identify CRC recurrence. We estimated the effect of misclassifying recurrence on survival by applying these findings to the linked Surveillance, Epidemiology, and End Results-Medicare data. Of 174 eligible CRC patients identified through medical records, 32 (18.4%) had a recurrence. A claims-based algorithm of secondary malignancy codes yielded a sensitivity of 81% and specificity of 99% for identifying recurrence. Agreement between data sources was almost perfect (kappa: 0.86). In a model unadjusted for misclassification, CRC patients with recurrence were 3.04 times (95% confidence interval: 2.92-3.17) more likely to die of any cause than those without recurrence. In the corrected model, CRC patients with recurrence were 3.47 times (95% confidence interval: 3.06-4.14) more likely to die than those without recurrence. Identifying recurrence in CRC patients using c...Continue Reading

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Citations

Nov 20, 2015·Journal of the National Cancer Institute·Candyce H KroenkeBette J Caan
May 15, 2015·Journal of the National Cancer Institute·Joan L Warren, K Robin Yabroff
Oct 6, 2018·Pharmacoepidemiology and Drug Safety·Jennifer W WuKristian B Filion
Dec 13, 2018·Journal of the American Medical Informatics Association : JAMIA·Alpha Oumar DialloWendy Book
Jan 18, 2019·JCO Clinical Cancer Informatics·Hajime UnoMichael J Hassett
Apr 8, 2020·Journal of the National Cancer Institute·Hava IzciPatrick Neven
Apr 22, 2021·International Journal of Epidemiology·Julie M PetersenMatthew P Fox
Oct 5, 2021·Frontiers in Oncology·Zi-Xin WuZhe-Xiong Lian

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