Development of a clinical algorithm for treating urethral strictures based on a large retrospective single-center cohort

F1000Research
Yuri TolkachFlorian Imkamp

Abstract

Aim: To analyze clinical data from male patients treated with urethrotomy and to develop a clinical decision algorithm. Materials and methods: Two large cohorts of male patients with urethral strictures were included in this retrospective study, historical (1985-1995, n=491) and modern cohorts (1996-2006, n=470). All patients were treated with repeated internal urethrotomies (up to 9 sessions). Clinical outcomes were analyzed and systemized as a clinical decision algorithm. Results: The overall recurrence rates after the first urethrotomy were 32.4% and 23% in the historical and modern cohorts, respectively. In many patients, the second procedure was also effective with the third procedure also feasible in selected patients. The strictures with a length ≤ 2 cm should be treated according to the initial length. In patients with strictures ≤ 1 cm, the second session could be recommended in all patients, but not with penile strictures, strictures related to transurethral operations or for patients who were 31-50 years of age. The third session could be effective in selected cases of idiopathic bulbar strictures. For strictures with a length of 1-2 cm, a second operation is possible for the solitary low-grade bulbar strictures, giv...Continue Reading

References

Jan 1, 1995·International Urology and Nephrology·M IshigookaK Mitobe
Feb 14, 2006·Nature Clinical Practice. Urology·André M Naudé, Chris F Heyns
Jul 27, 2010·Journal of Endourology·Milos BrodakLukas Holub
Dec 14, 2012·The Cochrane Database of Systematic Reviews·Susan S W WongRobert Pickard
Dec 19, 2013·Nature Reviews. Urology·Lindsay A HampsonBenjamin N Breyer
Dec 24, 2013·Urology·Enzo PalminteriFrancesco Rocco

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Citations

May 27, 2020·World Journal of Urology·Athul John, Arman A Kahokehr
Jan 30, 2020·Revista da Associação Médica Brasileira·Ahmet UrkmezMetin Ishak Ozturk

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