Development of a conceptual framework of health-related quality of life in locally recurrent rectal cancer

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
D P HarjiJ Brown

Abstract

The surgical management of locally recurrent rectal cancer (LRRC) has become widely accepted to afford cure and improve quality of life in this subset of patients. Thus far, traditional surgical and oncological markers have been used to highlight the success of surgical intervention. The use of patient-reported outcomes, specifically health-related quality of life (HRQoL), is sparse in these patients. This may be in part due to the lack of well-designed, validated instruments. This study identifies HRQoL issues relevant to patients undergoing surgery for LRRC, with the aim of developing a conceptual framework of HRQoL specific to LRRC to enable measurement of patient-reported outcomes in this cohort of patients. Qualitative focus groups were undertaken at two institutions to identify relevant HRQoL themes. The principles of thematic content analysis were used to analysis data. NViVo10 was used to analyse data. Twenty-one patients participated in six consecutive focus groups. Two patterns of themes emerged related to HRQoL and healthcare service delivery and utilization. Identified themes related to HRQoL included symptoms, sexual function, psychological impact, role and social functioning and future perspective. Under healthcar...Continue Reading

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Citations

Feb 21, 2021·The British Journal of Surgery·M J Solomon
Mar 19, 2021·European Journal of Cancer Care·Chloe Yi Shing LimPhyllis Butow
Apr 3, 2021·Surgical Oncology·Kheng-Seong Ng, Peter J M Lee
Apr 28, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Matthew R FahyDes C Winter

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