Development of a core outcome set for pediatric critical care outcomes research.

Contemporary Clinical Trials
Ericka L FinkEunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Resear

Abstract

Pediatric Intensive Care Unit (PICU) teams provide care for critically ill children with diverse and often complex medical and surgical conditions. Researchers often lack guidance on an approach to select the best outcomes when evaluating this critically ill population. Studies would be enhanced by incorporating multi-stakeholder preferences to better evaluate clinical care. This manuscript outlines the methodology currently being used to develop a PICU Core Outcome Set (COS). This PICU COS utilizes mixed methods, an inclusive stakeholder approach, and a modified Delphi consensus process that will serve as a resource for PICU research programs. A Scoping Review of the PICU literature evaluating outcomes after pediatric critical illness, a qualitative study interviewing PICU survivors and their parents, and other relevant literature will serve to inform a modified, international Delphi consensus process. The Delphi process will derive a set of minimum domains for evaluation of outcomes of critically ill children and their families. Delphi respondents include researchers, multidisciplinary clinicians, families and former patients, research funding agencies, payors, and advocates. Consensus meetings will refine and finalize the do...Continue Reading

Citations

Sep 2, 2020·American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses·Nora FayedKaren Choong
Aug 1, 2020·Paediatric Anaesthesia·Wallis T MuhlyUNKNOWN Pediatric Perioperative Outcomes Group
Oct 14, 2020·Critical Care Medicine·Ericka L FinkUNKNOWN Pediatric Outcomes STudies after PICU (POST-PICU) Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators
Oct 4, 2020·Critical Care Medicine·Aline B MadduxUNKNOWN Pediatric Outcomes STudies after PICU (POST-PICU) and PICU-COS Investigators of the Pediatric Acute Lung Injury and Sepsis I
Jun 30, 2021·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Elizabeth Y KillienUNKNOWN POST-PICU and PICU-COS Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators and the Eunice Kennedy Shri

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