Development of a core outcome set for studies on prevention and management of pregnancy-associated venous thromboembolism (COSPVenTE): a study protocol.

BMJ Open
Alexandria KingAnn K Malinowski

Abstract

Pregnancy and post partum are times of heightened risk for the development of venous thromboembolism (VTE), which in turn is one of the leading causes of maternal mortality and long-term morbidity. The current research aimed at improving health guidelines for women with pregnancy-associated VTE is limited by inconsistency in outcome reporting preventing comparison across studies, and lack of input from patients with respect to outcomes they propose are most important to measure. A suggested solution is the development of a core outcome set (COS) that defines the minimum criteria for outcome reporting in clinical trials and prospective studies. COSs function to facilitate data harmonisation and increase homogeneity in outcome reporting while incorporating the voice of women in this population in the planning of research to inform their ongoing care. The development of a COS for studies on pregnancy-associated VTE will comprise five steps. First, a systematic review of the published literature will identify currently reported outcomes, their definitions and measurements if applicable. This will be followed by in-person interviews with patients, clinicians, researchers, hospital administrators and policy-makers to identify outcome...Continue Reading

Citations

Mar 10, 2021·BJOG : an International Journal of Obstetrics and Gynaecology·A CiociR Rattan
Oct 11, 2021·BMC Pregnancy and Childbirth·Marie ÖsterbergMaria Jonsson

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Software Mentioned

CoRe
STAndards
OVidSP
NGT
COS
COMET
COSPVenTE
Delphi Manager

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