Development of a frailty index for patients with coronary artery disease

Journal of the American Geriatrics Society
Elizabeth A FreiheitColleen J Maxwell

Abstract

To construct a brief frailty index for older patients with coronary artery disease (CAD) undergoing coronary angiography that includes physical, cognitive, and psychosocial criteria and accurately predicts future disability and decline in health-related quality of life (HRQL). Prospective cohort. An urban tertiary care hospital in Alberta, Canada. Three hundred seventy-four patients aged 60 and older (73% male) undergoing cardiac catheterization for CAD between October 2003 and May 2007. Potential frailty criteria examined at baseline (before the procedure) included measures of balance, gait speed, cognition, self-reported health, body mass index (BMI), depressive symptoms, and living alone. The outcomes assessed over 1 year were dependency in activities of daily living (ADLs) and HRQL. The five best-fitting criteria from regression analyses for ADL decline were poor balance (risk ratio (RR)=2.4, 95% confidence interval (CI)=1.4–4.0), abnormal BMI (RR=1.8, 95% CI=1.1–3.0), impaired Trail-Making Test Part B performance (RR=2.3, 95% CI=1.3–4.2), depressive symptoms (RR=1.8, 95% CI=1.1–3.1), and living alone (RR=2.2, 95% CI=1.3–3.8). Using the five criteria as separate variables or as a summary frailty index yielded identical area...Continue Reading

References

Dec 1, 1996·Journal of Clinical Epidemiology·P PeduzziA R Feinstein
Jun 12, 1998·JAMA : the Journal of the American Medical Association·B W PenninxR B Wallace
Mar 23, 2004·American Journal of Epidemiology·Guangyong Zou
Jun 7, 2005·Journal of the American Geriatrics Society·Caroline S BlaumLinda P Fried
Dec 6, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Erica I LubetkinMarthe R Gold
Mar 1, 2006·Archives of Internal Medicine·Thomas M GillLing Han
Nov 8, 2006·Journal of the American Geriatrics Society·Jama L PurserKaren P Alexander
Apr 20, 2007·Journal of General Internal Medicine·Heidi N SchmaltzColleen J Maxwell
May 12, 2007·Journal of the American Geriatrics Society·Gail J McAvaySharon K Inouye
Oct 9, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Julene K JohnsonKristine Yaffe
Jul 23, 2008·International Journal of Clinical Practice·M KanauchiY Saito
Dec 20, 2008·Journal of the American Geriatrics Society·Marc D RothmanThomas M Gill
Feb 28, 2009·Journal of the American Geriatrics Society·Kristine E EnsrudUNKNOWN Osteoporotic Fractures in Men Research Group
Feb 28, 2009·Journal of the American Geriatrics Society·José Alberto Avila-FunesJean-François Dartigues
May 26, 2009·The American Journal of Cardiology·Jonathan AfilaloHoward Bergman

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Citations

May 4, 2013·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Nadia SourialJack Guralnik
Jun 22, 2013·BMC Geriatrics·Kim BouillonG David Batty
Sep 29, 2011·Current Cardiovascular Risk Reports·Jonathan Afilalo
Nov 5, 2013·The Canadian Journal of Cardiology·Michelle M GrahamColleen M Norris
May 9, 2012·The Annals of Thoracic Surgery·Roberto CerveraDanny Chu
Dec 9, 2015·Aging Clinical and Experimental Research·Shogo FukuiMeigen Liu
Nov 19, 2011·Journal of the American Geriatrics Society·Shelley A SternbergA Mark Clarfield
Feb 15, 2011·Journal of the American Geriatrics Society·Dae Hyun Kim, Sung Eun Choi
Apr 16, 2011·Journal of the American Geriatrics Society·Briana Mezuk
Dec 23, 2014·Cancer·Kirsten K NessJames L Kirkland
Nov 28, 2013·International Journal of Cardiology·Vicki MyersYariv Gerber
Oct 3, 2012·European Journal of Preventive Cardiology·Vicki MyersUNKNOWN Israel Study Group on First Acute Myocardial Infarction
Nov 22, 2014·Journal of Aging and Health·David Basic, Chris Shanley
Dec 4, 2016·Biological Research for Nursing·Deborah A LekanHeather E Whitson
Jun 22, 2017·American Journal of Epidemiology·Gloria A AguayoDaniel R Witte
Aug 31, 2018·The Journal of International Medical Research·J BurkauskasN Mickuvienė
May 12, 2016·Circulation. Cardiovascular Quality and Outcomes·Elizabeth A FreiheitColleen J Maxwell
Dec 28, 2018·Journal of the American Geriatrics Society·Jennifer L SuttonRobert J Howard
Jun 13, 2017·Cardiology in Review·Gautam VermaWilliam H Frishman
Apr 30, 2019·PloS One·Jossiana Wilke FallerSilvia Matumoto
Sep 3, 2013·Current Opinion in Critical Care·Sean M Bagshaw, Robert C McDermid
Aug 17, 2012·Expert Review of Cardiovascular Therapy·Karen HarknessRobert S McKelvie
Sep 7, 2019·Aging Clinical and Experimental Research·Shaomin ZhangJinhui Wu
Nov 22, 2011·Journal of Nutrition in Gerontology and Geriatrics·Roschelle A Heuberger
Jul 6, 2017·Intensive Care Medicine·John MuscedereKenneth Rockwood
Oct 4, 2017·Pharmacy : Journal of Pharmacy, Education and Practice·Christopher HarlowHolly Divine
Oct 2, 2019·Journal of Clinical Medicine·Hiroyuki ShimadaHidenori Arai
Apr 13, 2021·Journal of Epidemiology·Mari YamashitaShoji Shinkai

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