PMID: 18415986Apr 17, 2008Paper

Development of a new bioprocess for production of 1,3-propanediol I.: Modeling of glycerol bioconversion to 1,3-propanediol with Klebsiella pneumoniae enzymes

Applied Biochemistry and Biotechnology
Aron Németh, Béla Sevella

Abstract

Glycerol is a renewable resource for it is formed as a byproduct during biodiesel production. Because of its large volume production, it seems to be a good idea to develop a technology that converts this waste into products of high value, for example, to 1,3-propanediol (1,3-PD). We suggested an enzymatic bioconversion in a membrane reactor in which the NAD coenzyme can be regenerated, and three key enzymes are retained by a 10-kDa ultrafilter membrane. Unfortunately, some byproducts also formed during successful glycerol to 1,3-PD bioconversion runs, as we used crude enzyme solution of Klebsiella pneumoniae. To study the possibilities to avoid this byproduct formation, we built a mathematical description of this system. The model was also used for simulation bioconversions of high glycerol concentration with and without elimination of byproduct formation and of continuous operation.

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Citations

May 30, 2009·Applied Biochemistry and Biotechnology·Karina B Hueso DomínguezAntónio O S S Rangel
Jul 31, 2013·Bioprocess and Biosystems Engineering·Fatma Gizem AvciNuri Azbar
Jun 10, 2011·Applied Microbiology and Biotechnology·Filipa Soares MendesIsabel Vasconcelos
Aug 12, 2009·Biotechnology Advances·R K SaxenaJasmine Isar
Oct 21, 2016·Applied Microbiology and Biotechnology·Meng WangTianwei Tan
May 15, 2012·Applied Microbiology and Biotechnology·Afroditi Chatzifragkou, Seraphim Papanikolaou
Mar 6, 2008·Applied Microbiology and Biotechnology·Zhi-Long Xiu, An-Ping Zeng
Oct 15, 2011·Critical Reviews in Biotechnology·E Celińska
Apr 7, 2010·Biotechnology Advances·E Celińska

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