Development of a Novel Self-administered Cognitive Assessment Tool and Normative Data for Older Adults

Journal of Neurosurgical Anesthesiology
Raphael J MonschNicolai Goettel

Abstract

Preexisting cognitive impairment in surgical patients is one of the leading risk factors for adverse cognitive outcomes such as postoperative delirium and postoperative cognitive dysfunction. We developed a self-administered tablet computer application intended to assess the individual risk for adverse postoperative cognitive outcomes. This cross-sectional study aimed to establish normative data for the tool. Healthy volunteers aged 65 years and above were administered the Mini-Mental State Examination, Geriatric Depression Scale, and Consortium to Establish a Registry for Alzheimer's Disease-Neuropsychological Assessment Battery to assess cognitive health. All subjects completed the tablet computer application without assistance. Primary outcome measure was the test performance. Regression models were built for each cognitive domain score with the covariates age, sex, and education in cognitively healthy subjects. Demographically adjusted standard scores (z-scores) were computed for each subtest. A total of 283 participants (155 women, 128 men) were included in the final analysis. Participants' age was 73.8±5.2 years (mean±SD) and their level of education was 13.6±2.9 years. Mini-Mental State Examination score was 29.2±0.9 poi...Continue Reading

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Citations

Jan 22, 2019·Journal of Neurosurgical Anesthesiology·Nicolai Goettel
Jan 24, 2020·Journal of Neurosurgical Anesthesiology·Jeffrey J Pasternak
Dec 10, 2020·Acta Anaesthesiologica Scandinavica·Richard A BuckleyLisbeth Evered
Jan 23, 2021·Journal of Neurosurgical Anesthesiology·Jeffrey J Pasternak
May 7, 2021·Journal of Medical Internet Research·Riley CapizziSophia Vinogradov
Nov 24, 2021·Acta Anaesthesiologica Scandinavica·Richard A BuckleyLisbeth Evered

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Clinical Trials Mentioned

NCT02708823

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CogCheck
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