Development of a novel shrouded impeller pediatric blood pump

Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs
Talha Irfan KhanOzlem Yalcin

Abstract

The aim of this work was to analyze a shrouded impeller pediatric ventricular assist device (SIP-VAD). This device has distinctive design characteristics and parameter optimizations for minimization of recirculation flow and reduction in high-stress regions that cause blood damage. Computational Fluid Dynamics (CFD) simulations were performed to analyze the optimized design. The bench-top prototype of SIP-VAD was manufactured with biocompatible stainless steel. A study on the hydrodynamic and hemodynamic performance of the SIP-VAD was conducted with predictions from CFD and actual experimentation values, and these results were compared. The CFD analysis yielded a pressure range of 29-90 mmHg corresponding to flow rates of 0.5-3 L/min over 9000-11000 rpm. The predicted value of the normalized index of hemolysis (NIH) was 0.0048 g/100 L. The experimental results with the bench-top prototype showed a pressure rise of 30-105 mmHg for the flow speed of 8000-12000 rpm and flow rate of 0.5-3.5 L/min. The maximum difference between CFD and experimental results was 4 mmHg pressure. In addition, the blood test showed the average NIH level of 0.00674 g/100 L. The results show the feasibility of shrouded impeller design of axial-flow pump ...Continue Reading

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Citations

Feb 24, 2019·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Y SawaT Yamaoka
Jun 20, 2019·Artificial Organs·Jamshid H KarimovTakuma Miyamoto
Sep 23, 2020·The International Journal of Artificial Organs·Zheqin YuBin Guo
Oct 13, 2018·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Behnam GhadimiNasim Naderi
Oct 4, 2019·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Ismail LazogluSevket Ruacan

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