PMID: 9639607Jun 26, 1998Paper

Development of a pediatric liver transplantation program in Argentina

Pediatric Surgery International
E WilliamsO Imventarza

Abstract

This article describes the preliminary experimental steps and clinical implementation of a purely pediatric liver transplantation (LT) program in a large public children's hospital in Buenos Aires, Argentina, a city with well over 10 million inhabitants and a referral population of over 30 million. Between 1993 and 1997, 84 LTs were performed in 81 patients, of which one-fourth weighed below 10 kg. The main indications were biliary atresia (n = 25, 30%) and fulminant liver failure (n = 23, 27%), followed by autoimmune cirrhosis (n = 14, 16%) and other liver diseases. Shortage of organs due to local conditions led to the use of liver-reduction techniques in 48 cases (57%), split liver in 2, and living-related donor (LRD) in 2. Retransplantation was necessary in 3 instances. Seventy-eight percent of the recipients survived for more than 1 year and 71% were alive after 4 years. The authors comment on the need for adaptation to local conditioning factors when developing a pediatric LT program in any country in which demographics and economic, medical, and sociological environments have a decisive influence on organ procurement, the actual performance of the operation, and the lifelong postoperative medication. In Buenos Aires, wher...Continue Reading

Citations

Sep 13, 2007·The Pediatric Infectious Disease Journal·Mirta CioccaJohn Weil
May 23, 2006·Pediatric Transplantation·Mariana del PinoHoracio Lejarraga
Apr 14, 2007·Pediatric Transplantation·Seyed Mohsen DehghaniSeyed Ali Malek-Hosseini
Oct 22, 2008·Journal of Viral Hepatitis·C T FerreiraT R Silveira

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