Abstract
Self-expandable metal stent (SEMS) positioning is the recommended method for palliation of dysphagia from esophageal cancer, although it is not adverse event-free. The present study was aimed at identifying predictors for adverse events and at proposing a statistical model to predict them. We performed a retrospective analysis of a prospectively collected database. All patients who underwent SEMS placement for stricture due to esophageal cancer between 2002 and 2011 in a tertiary-care center were identified. Multivariable regression analysis in the presence of competing risk events was used to identify factors associated with SEMS-related adverse events and to build a prediction model. A total of 267 patients were included. According to the competing risk regression analysis, only 2 variables were significantly associated with the risk of SEMS-related adverse events: prior chemoradiotherapy (CRT), yielding a hazard ratio (HR) of 1.687 (95% confidence interval [CI], 1.076-2.644), and the SEMS length (HR 0.884; 95% CI, 0.798-0.980) for every 10-mm length increase. Based on the estimated probability curves, after 4 months from SEMS placement, the probability of an adverse event in patients who did receive prior CRT was 50.9% compa...Continue Reading
References
Dec 1, 1982·Gut·A L OgilvieM Atkinson
Jun 1, 1996·Gastrointestinal Endoscopy·N BethgeN Vakil
Mar 1, 1996·Gastrointestinal Endoscopy·K J KinsmanJ Rosch
Jul 21, 2001·Japanese Journal of Clinical Oncology·M MutoS Yoshida
Apr 13, 2004·European Journal of Gastroenterology & Hepatology·Marjolein Y V HomsPeter D Siersema
Jun 16, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ian ChauPaul J Ross
Oct 27, 2004·Lancet·Marjolein Y V HomsPeter D Siersema
Apr 13, 2005·Endoscopy·U WengerJ Lagergren
Aug 23, 2005·Gastrointestinal Endoscopy·Ewout W SteyerbergUNKNOWN SIREC Study Group
Jul 5, 2006·Alimentary Pharmacology & Therapeutics·S LecleireP Michel
Sep 9, 2006·Radiation Medicine·Yuko IrahaNoboru Tanigawa
Dec 23, 2006·Gastrointestinal Endoscopy·William A RossMike Bismar
Nov 15, 2011·European Journal of Gastroenterology & Hepatology·Atsushi YagishitaHiroyuki Ono
Jun 5, 2012·Gastrointestinal Endoscopy·Paul DiddenMarco J Bruno
Dec 19, 2012·Gastrointestinal Endoscopy·Benjamin L BickMark D Topazian
Feb 5, 2013·Lancet·Arjun PennathurJames D Luketich
Jun 20, 2013·Endoscopy·M EllrichmannA Fritscher-Ravens
Feb 5, 2014·Biostatistics·Marcel WolbersThomas A Gerds
Oct 17, 2014·Gut·Melina ArnoldDavid Forman
Citations
Mar 16, 2016·Gastrointestinal Endoscopy·Wouter F W Kappelle, Frank P Vleggaar
Mar 20, 2016·Current Treatment Options in Gastroenterology·Emanuele Dabizzi, Paolo Giorgio Arcidiacono
Aug 2, 2016·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Lorenzo FuccioAlessio Giuseppe Morganti
Sep 16, 2016·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·E Rodrigues-PintoG Macedo
Oct 13, 2016·Gut and Liver·Hiroyasu IwasakiHitoshi Sano
Jan 6, 2017·Gut and Liver·Ji Bong Jeong, Dong-Won Ahn
Dec 28, 2016·Gastrointestinal Endoscopy·Vitor Sousa MedeirosFauze Maluf-Filho
Jan 21, 2017·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Lorenzo FuccioAlessio Giuseppe Morganti
Jan 26, 2017·ACG Case Reports Journal·Giuseppe GrandeRita Conigliaro
Oct 7, 2019·Abdominal Radiology·Nader BakheetHo-Young Song
Feb 9, 2018·PloS One·H G van den BoornH W M van Laarhoven
May 31, 2019·Cardiovascular and Interventional Radiology·Chao WangJin-He Guo
Nov 7, 2019·Nanomaterials·Kateřina ŠkrlováDaniela Plachá
Dec 18, 2019·BMC Gastroenterology·Dae Hwan KangHyeong Seok Nam
Nov 28, 2019·Dysphagia·Juan QinGao-Jun Teng
May 1, 2021·Endoscopy·Manon C W SpaanderJeanin E van Hooft
Oct 27, 2018·Acta Biomaterialia·Maohua LinYunqing Kang