PMID: 18209890Jan 23, 2008Paper

Development of a semi-automated method for measuring urinary iodine and its application in epidemiological studies in Brazilian schoolchildren

Arquivos brasileiros de endocrinologia e metabologia
Roberto Z EstevesRui M B Maciel

Abstract

In this study we developed a semi-automated method for the measurement of urinary iodine using firstly ammonium persulfate for digestion of urine followed by estimation of iodine content in the Sandell-Kolthoff reaction, in which iodine acts as a catalyst for the reduction of cerium. This method was validated in the 3rd Brazilian National Survey of iodine deficiency in 1994. We studied 16,803 casual urine samples from schoolchildren of 401 cities and found 4 moderately-deficient towns (Almas, Arraias, and Parana, in the State of Tocantins, and Cocos, in the State of Bahia), and 116 mildly-deficient. This work suggests that despite the salt iodization program, there was some iodine-deficient areas in Brazil in 1994. Recent surveys, involving less cities, are indicating an excess of iodine ingestion. Therefore, in a country of continental dimensions and very heterogeneous in terms of public health, periodical evaluations are necessary to monitor the real situation of iodine nutrition in Brazil. The method developed in this paper is suitable for these surveys.

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Citations

Oct 5, 2010·Thyroid : Official Journal of the American Thyroid Association·José A SgarbiRui M B Maciel
May 31, 2012·Journal of Clinical Immunology·Maria Angela Zaccarelli-Marino
May 18, 2016·Thyroid : Official Journal of the American Thyroid Association·Renata de Oliveira CamposHelton Estrela Ramos
Aug 4, 2009·Arquivos brasileiros de endocrinologia e metabologia·Geraldo Medeiros-Neto
Oct 26, 2018·Thyroid : Official Journal of the American Thyroid Association·Maria Lúcia D'Arbo AlvesAnderson Marliere Navarro
Sep 22, 2019·International Journal of Environmental Research and Public Health·Maria Angela Zaccarelli-MarinoMarco Antonio Garcia Martins
Apr 7, 2009·Arquivos brasileiros de endocrinologia e metabologia·Alana Abrantes Nogueira de PontesLuís Fernando Fernandes Adan
May 1, 2009·International Journal of Surgical Pathology·Ana Maria de Oliveira RamosLaura Sterian Ward
Jan 10, 2014·Arquivos brasileiros de endocrinologia e metabologia·Paulo César Ribeiro BoasquevisqueCarlos Musso
Nov 24, 2016·International Journal of Environmental Research and Public Health·Maria Angela Zaccarelli-MarinoJulio M Singer
Apr 7, 2009·Arquivos brasileiros de endocrinologia e metabologia·Maria Angela Zaccarelli MarinoRui M B Maciel
Apr 21, 2020·Biological Trace Element Research·Renata de Oliveira Campos, Helton Estrela Ramos

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