Development of a standardized chart review method to identify drug-related hospital admissions in older people

British Journal of Clinical Pharmacology
Stefanie ThevelinOlivia Dalleur

Abstract

We aimed to develop a standardized chart review method to identify drug-related hospital admissions (DRA) in older people caused by non-preventable adverse drug reactions and preventable medication errors including overuse, underuse and misuse of medications: the DRA adjudication guide. The DRA adjudication guide was developed based on design and test iterations with international and multidisciplinary input in four subsequent steps: literature review; evaluation of content validity using a Delphi consensus technique; a pilot test; and a reliability study. The DRA adjudication guide provides definitions, examples and step-by-step instructions to measure DRA. A three-step standardized chart review method was elaborated including: (i) data abstraction; (ii) explicit screening with a newly developed trigger tool for DRA in older people; and (iii) consensus adjudication for causality by a pharmacist and a physician using the World Health Organization-Uppsala Monitoring Centre and Hallas criteria. A 15-member international Delphi panel reached consensus agreement on 26 triggers for DRA in older people. The DRA adjudication guide showed good feasibility of use and achieved moderate inter-rater reliability for the evaluation of 16 cas...Continue Reading

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Citations

Oct 22, 2018·European Journal of Clinical Pharmacology·Christina Raae HansenLaura J Sahm
Dec 27, 2018·International Journal of Clinical Pharmacy·Thomas G H KempenUlrika Gillespie
Dec 4, 2020·British Journal of Clinical Pharmacology·Greet Van De SijpeLorenz Van der Linden
Feb 21, 2021·British Journal of Clinical Pharmacology·Johan LönnbroSusanna M Wallerstedt
Mar 26, 2021·International Journal of Clinical Pharmacy·Martina MaříkováJiří Vlček
Aug 21, 2021·Research in Social & Administrative Pharmacy : RSAP·Myriam JaamMaguy Saffouh El Hajj
Sep 7, 2021·International Journal of Clinical Practice·Tristan CoppesFatma Karapinar-Çarkit
Jan 23, 2022·Journal of the American Geriatrics Society·Carole E AubertJacques Donzé

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