Development of a transplantation transmission sentinel network to improve safety and traceability of organ and tissues

Cell and Tissue Banking
D Michael StrongMatthew J Kuehnert

Abstract

The US lags behind other developed countries in creating a system to monitor disease transmission and other complications from human allograft use, despite a pressing need. The risks of transmission are amplified in transplantation, since at least 8 organs and more than 100 tissues can be recovered from a single common organ and tissue donor. Moreover, since many allografts collected in the US are distributed internationally, tissue safety is a global concern. In June 2005, participants of a US government-sponsored workshop concluded that a communication network for the tracking and reporting of disease transmissions for tissues and organs was critically needed. The United Network for Organ Sharing (UNOS) entered into a cooperative agreement with the Centers for Disease Control and Prevention (CDC) in 2006 to develop a system prototype. Over the following 3 years, the Transplantation Transmission Sentinel Network (TTSN) was developed and piloted with the participation of organ procurement organizations, tissue banks and transplant centers. The prototype centered around three elements of data entry: (1) donation, (2) tissue implantation, and (3) adverse event. The pilot proved that a system can be built and operated successfully...Continue Reading

References

Nov 3, 2005·Annals of Internal Medicine·Barna D TugwellPaul R Cieslak
Dec 21, 2007·The New England Journal of Medicine·Jay A Fishman
Feb 13, 2008·Archives of Ophthalmology·Sohela S HassanUNKNOWN Medical Review Subcommittee of the Eye Bank Association of America
Sep 16, 2008·Annals of Surgery·Jayme E LockeAndrew M Cameron
Nov 20, 2008·Cell and Tissue Banking·Jay A FishmanMatthew J Kuehnert
Jun 23, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M G IsonM Nalesnik

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Citations

Nov 28, 2013·Cell and Tissue Banking·Reena Mahajan, Matthew J Kuehnert
Oct 26, 2010·Cell and Tissue Banking·D Michael Strong, Rüdiger von Versen
Dec 23, 2011·MMWR. Morbidity and Mortality Weekly Report·UNKNOWN Centers for Disease Control and Prevention (CDC)
Mar 8, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S A FischerUNKNOWN AST Infectious Diseases Community of Practice
Jul 2, 2017·Cell and Tissue Banking·D Michael Strong
Oct 28, 2019·Perspectives in Clinical Research·Sukhjinder SinghBikash Medhi

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