Development of advanced macrosphelides: potent anticancer agents

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Seung-Mann Paek

Abstract

Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography preparation. In addition, advances in their apoptosis-inducing activities are also included.

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Oct 10, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Seung-Mann Paek

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Citations

Jul 5, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Katarzyna WińskaMirosław Anioł
May 21, 2018·Journal of Natural Medicines·Satoshi Takamatsu

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Methods Mentioned

BETA
X-ray
amidation
flow cytometry

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

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