Development of ambient sampling chemi/chemical ion source with dielectric barrier discharge

Journal of Mass Spectrometry : JMS
Lee Chuin ChenKenzo Hiraoka

Abstract

The development of a new configuration of chemical ionization (CI)-based ion source is presented. The ambient air containing the gaseous sample is sniffed into an enclosed ionization chamber which is of sub-ambient pressure, and is subsequently mixed with metastable species in front of the ion inlet of the mass spectrometer. Metastable helium atoms (He*) are used in this study as the primary ionizing agents and are generated from a dielectric barrier discharge (DBD) source. The DBD is powered by an AC high-voltage supply and the configuration of the electrodes is in such a way that the generated plasma is confined within the discharge tube and is not extended into the ionization chamber. The construction of the ion source is simple, and volatile compounds released from the bulky sample can also be analyzed directly by approaching the sample to the sampling nozzle. When combined with heated nitrogen or other desorption methods, its application can also be extended to non-volatile compounds, and the consumption for helium can be kept minimum solely for maintaining the stable discharge and gas phase ionization. Applications to non-proximate sample analysis, direct determination of active ingredients in drug tablets and the detecti...Continue Reading

References

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Aug 27, 2004·Rapid Communications in Mass Spectrometry : RCM·Song PengJoachim Franzke
Sep 24, 2004·Rapid Communications in Mass Spectrometry : RCM·Kenzo HiraokaShigemitsu Okazaki
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Citations

Jan 11, 2013·Chemical Reviews·María Eugenia MongeFacundo M Fernández
Feb 18, 2016·Journal of the American Society for Mass Spectrometry·Joel D KeelorFacundo M Fernández
May 20, 2015·Mass Spectrometry Reviews·Marek SmoluchJerzy Silberring
Apr 18, 2013·Rapid Communications in Mass Spectrometry : RCM·Masuyuki SugiyamaYuichiro Hashimoto
Mar 16, 2013·Journal of Mass Spectrometry : JMS·Lee Chuin ChenKenzo Hiraoka
Mar 16, 2013·Rapid Communications in Mass Spectrometry : RCM·Mario BenassiBernhard Spengler
Sep 10, 2015·Rapid Communications in Mass Spectrometry : RCM·Matthew CurtisFacundo M Fernández
Jul 28, 2015·Rapid Communications in Mass Spectrometry : RCM·Ahsan HabibKenzo Hiraoka
Dec 17, 2014·Analytical and Bioanalytical Chemistry·Cheng'an GuoXinrong Zhang
Jun 16, 2017·The Analyst·Lee Chuin ChenKenzo Hiraoka
Aug 31, 2017·Mass Spectrometry·Lee Chuin ChenKenzo Hiraoka
Apr 19, 2011·Analytical Chemistry·Glenn A HarrisFacundo M Fernández

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