Development of body proportions in achondroplasia: Sitting height, leg length, arm span, and foot length

American Journal of Medical Genetics. Part a
Andrea MerkerLars Hagenäs

Abstract

The aims of this study was to construct references for sitting height, leg length, arm span, relative sitting height (sitting height/height), and foot length and to discuss the development for these anthropometric variables in achondroplasia. Sex-specific references covering ±2 SD are presented for ages 2-20 years. Legs and arms in achondroplasia are already at 2 years of age considerably shorter than in the general population and this deviation increases with age. At adult ages, legs are almost 50% shorter than in the general population and arm span roughly 35% shorter. As sitting height is only mildly affected, relative sitting height position develops far beyond normal ranges. Foot length is also not as affected as limbs.

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Citations

Jun 27, 2019·American Journal of Medical Genetics. Part a·Andrea MadsenHanne B Slettahjell
Jul 8, 2020·BMJ Open Respiratory Research·Karl Peter SylvesterKeith Butterfield
Mar 8, 2020·Wiener medizinische Wochenschrift·Wolfgang Högler, Leanne M Ward
Feb 13, 2020·Archives of Orthopaedic and Trauma Surgery·Antonio Leiva-GeaFelipe Luna-González
Nov 22, 2020·American Journal of Medical Genetics. Part a·Luitgard NeumeyerLars Hagenäs
Nov 13, 2020·Journal of Pediatric Endocrinology & Metabolism : JPEM·Mariana Del PinoPaula Adamo
Jan 1, 2021·American Journal of Medical Genetics. Part a·Olga Marieke de VriesSvein Otto Fredwall
Nov 19, 2020·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Svein O FredwallSerena Tonstad
Aug 26, 2021·Clinical Pharmacokinetics·Ming Liang ChanJoshua Henshaw
Jan 15, 2022·Journal of Bone and Mineral Metabolism·Hiroshi KitohKenta Sawamura

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