Development of carboxymethyl cellulose-based hydrogel and nanosilver composite as antimicrobial agents for UTI pathogens

Carbohydrate Polymers
Saad M AlshehriTansir Ahamad

Abstract

Silver nanoparticles (AgNPs) containing hydrogel composite were first synthesized by preparing a new hydrogel from carboxymethyl cellulose (CMC), polyvinyl alcohol (PVA), and the cross-linker ethylene glycol diglycidyl ether (EGDE), followed by the incorporation of AgNPs by microwave radiation. The resulting neat hydrogels and AgNPs-hydrogel composites were characterized using spectral, thermal, microscopic analysis and X-ray diffraction (XRD) analyses. The SEM and TEM results demonstrated that the synthesized AgNPs were spherical with diameters ranging from 8 to 14nm. In addition, the XRD analysis confirmed the nanocrystalline phase of silver with face-centered cubic (FCC) crystal structure. Energy dispersive spectroscopy (EDS) analysis of the AgNPs confirmed the presence of an elemental silver signal, and no peaks of any other impurities were detected. Additionally, the antibacterial activities of the neat hydrogel and AgNPs-hydrogel composites were measured by Kirby-Bauer method against urinary tract infection (UTI) pathogens. The rheology measurement revealed that the values of storage modulus (G') were higher than that of loss modulus (G″). The AgNPs-hydrogel composites exhibited higher antibacterial activity against Esche...Continue Reading

References

Feb 22, 2011·Chemical Communications : Chem Comm·Hamed Ataee-EsfahaniYusuke Yamauchi
Mar 18, 2011·Inorganic Chemistry·Daniel G MacDonaldJohn F Corrigan
Apr 20, 2011·Dental Materials : Official Publication of the Academy of Dental Materials·Jürgen DurnerFranx-Xaver Reichl
Jan 31, 2013·Physical Chemistry Chemical Physics : PCCP·Cuiling Li, Yusuke Yamauchi
Sep 26, 2013·International Journal of Biological Macromolecules·B S AnishaR Jayakumar
Sep 26, 2014·Annals of Clinical Microbiology and Antimicrobials·Mohtaram NasrolaheiDavoud Esmaeili
Dec 3, 2014·International Journal of Biological Macromolecules·D ArchanaP K Dutta
Feb 25, 2015·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·P S RameshD Geetha
Mar 10, 2015·Materials Science & Engineering. C, Materials for Biological Applications·M Isabel González-SánchezPolina Prokopovich
Mar 24, 2015·International Journal of Biological Macromolecules·Abhijeet Mishra, Meryam Sardar
Mar 26, 2015·Indian Journal of Microbiology·Debadin Bose, Someswar Chatterjee
Apr 7, 2015·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·M MarzoukJ Boukadida
Apr 7, 2015·Journal of Pediatric Urology·N C BushW T Snodgrass
Apr 22, 2015·Annals of Clinical Microbiology and Antimicrobials·Hamdan Z HamdanIshag Adam
Apr 29, 2015·Aging Clinical and Experimental Research·Alice LaudisioRaffaele Antonelli Incalzi
Apr 29, 2015·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Wail A HayajnehRobert E Badal

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Citations

Apr 11, 2019·Polymers·Shabnam SattariMohsen Adeli
Oct 1, 2019·Global Challenges·Sadiya Anjum, Bhuvanesh Gupta
Jan 3, 2021·Advances in Colloid and Interface Science·Mahnaz AmiriMasoud Salavati-Niasari
Jun 8, 2018·Journal of Agricultural and Food Chemistry·Akbar Ali, Shakeel Ahmed

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