PMID: 6976513Nov 11, 1981Paper

Development of experimental sporotrichosis in normal and modified animals

Mycopathologia
H Hachisuka, Y Sasai

Abstract

The development of experimental sporotrichosis was examined in immunologically-disturbed mice. In the case of intracutaneous inoculation, the lesion in cyclophosphamide-treated mice enlarged strikingly up to 6 days, but at 12 days it was similar in size to that in non-treated mice. The lesion in irradiated mice developed slowly up to 12 days, but thereafter it developed promptly. In nude mice, the lesion was smallest during the development of the lesion. Histological examination showed that numerous organisms were present in the lesion of nude and irradiated mice. Intraperitoneal inoculation showed that dissemination of spores were easily induced in nude mice as compared with littermate mice. These results indicate an important role of cellular immunity in the defence mechanism of sporotrichosis.

References

Dec 16, 1977·Mycopathologia·M J Corbel, S M Eades
Aug 1, 1975·Infection and Immunity·P EmmerlingJ Bockemühl
Jun 1, 1975·Journal of the National Cancer Institute·N A SherJ H Vickers
Jan 11, 1976·The Journal of Clinical Investigation·R W SteeleL O Gentry
Jan 1, 1980·Dermatologica·H Hachisuka, Y Sasai

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Citations

Jul 23, 1982·Mycopathologia·H HachisukaY Sasai
Aug 29, 2001·Journal of Tongji Medical University = Tong Ji Yi Ke Da Xue Xue Bao·Z LiuJ Li
May 16, 2006·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Juan TanShaoru Zhang
Oct 1, 1985·Veterinary Immunology and Immunopathology·P F Lehmann
Apr 30, 2013·Comparative Immunology, Microbiology and Infectious Diseases·Luisa H M MirandaTânia M P Schubach
Oct 1, 1994·International Journal of Dermatology·A H Werner, B E Werner
Nov 28, 2012·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Semion Sukoriansky, Boris Galperin
Nov 1, 2017·Medical Mycology·Francine Alessandra ManenteIracilda Zeppone Carlos
Aug 12, 2009·Journal of Animal Physiology and Animal Nutrition·A SchiborraF Taube
Jan 1, 1986·Infection and Immunity·E N ScottD P Fine

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