PMID: 8608393Oct 1, 1995Paper

Development of mania in close association with tricyclic antidepressant administration in children. A report of two cases

European Child & Adolescent Psychiatry
J J BriscoeM Prendergast

Abstract

Two depressed children with a strong family history of affective disorder developed manic episodes shortly after starting treatment with low dose antidepressant therapy. In one of these cases manic symptoms appeared on each of the three occasions that tricyclic medication was started or increased in dosage. There are a few reports of manic switching in young people and one that describe such a close temporal association between the administration of antidepressants and the development of mania. Children with a family history of affective disorder may be more susceptible to manic switching.

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Citations

Oct 7, 2004·Journal of Affective Disorders·Gianni L FaeddaNancy B Austin
Jul 26, 2003·Journal of Child and Adolescent Psychopharmacology·Melissa P DelBelloStephen M Strakowski
Dec 29, 2009·Journal of Child and Adolescent Psychopharmacology·Cathryn A GalanterPeter S Jensen
Jan 1, 1998·International Journal of Psychiatry in Clinical Practice·C Tannock
Jun 22, 2011·Epilepsy & Behavior : E&B·Joseph Chien
May 5, 2006·Western Journal of Nursing Research·Alvita K Nathaniel
Jul 3, 2008·European Archives of Psychiatry and Clinical Neuroscience·David HealyJoanna Le Noury
Jan 10, 2018·The American Journal of Bioethics : AJOB·Elliott Mark Weiss, Autumn Fiester

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