Abstract
The lysozyme (LZ)-entrapped mannosylated liposomes were prepared in this study by the use of N-octadecyl-D-mannopyranosylamine (SAMAN), which had been synthesized in-house and confirmed by characterization with FTIR and NMR. The reactant residues of synthesized SAMAN were found to be less than 1%. The mean sizes, zeta potentials, drug entrapment efficiencies, and loading capacities of all liposomal formulations were in the ranges of 234.7 to 431.0 nm, -10.97 to -25.80 mV, 7.52 to 14.10%, and 1.44 to 2.77%, respectively. The permeability of mannosylated LZ liposomes across Caco-2 cell monolayers was significantly enhanced to about 2.5- and 7-folds over those of conventional liposomes and solution, respectively, which might be due to the role of mannose receptor or mannose-binding protein on the intestinal enterocytes.
References
Dec 1, 1977·Analytical Biochemistry·G L Peterson
Aug 1, 1992·Journal of Pharmaceutical and Biomedical Analysis·S RakotomangaD Baylocq-Ferrier
Mar 1, 1997·Pharmaceutical Research·A T Florence
Nov 5, 1999·International Journal of Pharmaceutics·G J Russell-JonesL Arthur
May 9, 2001·The Journal of Pharmacy and Pharmacology·Y H LiaoG P Martin
Oct 26, 2002·Journal of Controlled Release : Official Journal of the Controlled Release Society·Keon-Hyoung SongChang-Koo Shim
Dec 10, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Kazuhide UemuraToshisuke Kawasaki
Jan 23, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Swen WagnerMichael Loos
May 10, 2003·Journal of Controlled Release : Official Journal of the Controlled Release Society·Kenji YamabeYoshiharu Machida
Feb 19, 2004·Advanced Drug Delivery Reviews·Franz GaborMichael Wirth
Jun 28, 2005·Journal of Controlled Release : Official Journal of the Controlled Release Society·Keon-Hyoung SongChang-Koo Shim
Aug 30, 2005·International Journal of Pharmaceutics·Hirofumi TakeuchiYoshiaki Kawashima
Aug 1, 2006·Journal of Controlled Release : Official Journal of the Controlled Release Society·Wassana YeepraeMitsuru Hashida
Nov 15, 2006·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·B SarmentoM van de Weert
Nov 3, 2009·Colloids and Surfaces. B, Biointerfaces·Wasu WitoonsaridsilpChristel C Müller-Goymann
Jan 18, 2011·Current Drug Delivery·Boontarika BoonyapiwatSarinnate Kunastitchai
Citations
May 23, 2013·International Journal of Pharmaceutics·S E EltayebQineng Ping
May 7, 2015·Journal of Liposome Research·Koson YingsukwattanaNarong Sarisuta
Jan 27, 2016·International Journal of Pharmaceutics·Mohammad TariqSushama Talegaonkar
Apr 14, 2016·Nanomedicine·Thanh Xuan NguyenQun Wang
Jan 13, 2016·PloS One·Terrick AndeyMandip Singh
Nov 8, 2017·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Panita SuwannoiChristel C Müller-Goymann
Sep 28, 2018·PloS One·Jordan D LewickyHoang-Thanh Le
Jun 20, 2019·Pharmaceutics·Amolnat TunsirikongkonJeong-Sook Park
Jun 21, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·D GoyardR Roy
Nov 7, 2014·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Thanh Xuan NguyenGuang Yang
Dec 20, 2018·AAPS PharmSciTech·A B ShreyaSrinivas Mutalik
Oct 31, 2018·Open Life Sciences·Agnieszka Pudlarz, Janusz Szemraj