Development of Nonpulmonary Vein Foci Increases Risk of Atrial Fibrillation Recurrence After Pulmonary Vein Isolation

JACC. Clinical Electrophysiology
Rintaro HojoMasayasu Hiraoka

Abstract

The aim of this paper was to clarify the impact of nonpulmonary vein foci (NPVF) on atrial fibrillation (AF) recurrence after pulmonary vein (PV) isolation. NPVF are considered contributing factors for the recurrence of AF after PV isolation, but their exact role remains unclear. We retrospectively reviewed 216 patients (paroxysmal AF, n = 172; persistent AF, n = 44) who underwent a second electrophysiological study 6 months after the original PV isolation. Patients with AF recurrence underwent additional ablation procedures for reconnected PV and NPVF. NPVF were detected in the control group and with drug infusion (isoproterenol or isoproterenol with adenosine triphosphate) during the first and second procedure. NPVF detected for the first time in the second session were defined as newly developed, and their effect on AF recurrence after the second procedure was investigated, along with the predictive factors for NPVF development. Patients with AF recurrence after the first session had a significantly higher reconnected PV (91.5% vs. 68.2% in patients without recurrence). NPVF were detected in 20 and 54 patients in the first and second sessions, respectively. Patients with newly developed NPVF had a significantly higher AF rec...Continue Reading

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Citations

Aug 30, 2019·Arrhythmia & Electrophysiology Review·Nicolas JohnerDipen C Shah
Apr 10, 2020·Journal of Cardiovascular Electrophysiology·Rintaro HojoMasayasu Hiraoka
May 30, 2020·Journal of Cardiovascular Electrophysiology·Dai InagakiMasayasu Hiraoka
Dec 6, 2018·Current Opinion in Cardiology·Yenn-Jiang LinShih-Ann Chen
Mar 14, 2021·Journal of Cardiovascular Electrophysiology·Tomomasa TakamiyaTetsuo Sasano
May 6, 2021·Journal of Cardiovascular Electrophysiology·Shigeki KusaTetsuo Sasano

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