PMID: 7334148Nov 1, 1981Paper

Development of optimal treatment tactics for alcohol withdrawal. I. Assessment and effectiveness of supportive care

Journal of Clinical Psychopharmacology
J M ShawP Sandor

Abstract

The relative roles of supportive care and pharmacotherapy in the treatment of alcohol withdrawal are not established. A reliable and validated withdrawal severity assessment scale (Clinical Institute Withdrawal Assessment for Alcohol, CIWA-A) was developed to assess initially and then follow the clinical course of 38 hospitalized chronic alcoholics requiring hospitalization for withdrawal but without serious concurrent medical or surgical problems. Supportive care, consisting of standardized half-hourly patient assessment (CIWA-A) and nursing care, was used as the initial treatment for all patients. Twenty-eight (74%) patients with clinical supportive care successes within 8 hours, 75% within 4 hours. Two responding patients subsequently developed evidence of withdrawal at 48 hours (hallucinations) and 72 hours (seizure). Ten patients (26%) did not respond to supportive care and required drug therapy in addition. Responders to supportive care drink more by history and have less severe liver disease than nonresponders. There are no other apparent predictors of the patients who require drug therapy. Three quarters of hospitalized patients, without serious medical complications, in alcohol withdrawal respond to intensive supportiv...Continue Reading

Citations

Jan 1, 1992·European Archives of Psychiatry and Clinical Neuroscience·M BangerJ Aldenhoff
Nov 1, 1990·Emergency Medicine Clinics of North America·D B McMicken
Jul 1, 1996·Journal of General Internal Medicine·J A FergusonR S Dittus
Aug 1, 1994·Pharmacology, Biochemistry, and Behavior·P B DePetrillo
Jul 1, 1995·American Journal of Otolaryngology·A Alvi, R M Gonzalez
Jan 1, 1989·Progress in Neuro-psychopharmacology & Biological Psychiatry·S Radouco-ThomasG Stewart
Jan 1, 1983·Addictive Behaviors·M P McGovern, G C Caputo
Mar 1, 1986·Alcohol·D Butler, F S Messiha
Aug 1, 1997·Progress in Neuro-psychopharmacology & Biological Psychiatry·M SchmitzS Rudas
May 22, 2003·Drug and Alcohol Dependence·Kathleen T BradyJoseph V Brady
Jul 31, 1999·Drug and Alcohol Dependence·I B Crome
Jun 6, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Hans M OlbrichBernd Feige
Jun 20, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Rajita SinhaKristen M Siedlarz
Mar 1, 1997·Journal of Advanced Nursing·L Burns, M Adams
Aug 18, 1983·The New England Journal of Medicine·D J GreenblattD R Abernethy
Nov 22, 2002·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·David A FiellinRalph I Horwitz
Jan 4, 2003·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·David A. FiellinPatrick G. O'Connor
Jan 1, 1991·Drug and Alcohol Review·A Foy
Jan 1, 1991·Drug and Alcohol Review·E M Sellers, M K Romach
Sep 24, 2005·Journal of Nursing Care Quality·Janet Crumpler, Amelia Ross
Oct 13, 1990·BMJ : British Medical Journal·R Haigh, G Hibbert
Jun 28, 1997·Lancet·W Hall, D Zador
Jan 1, 1991·Drug and Alcohol Review·A Foy
Feb 15, 2008·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Michael SoykaUNKNOWN WFSBP Task Force on Treatment Guidelines for Substance Use Disorders
May 1, 1988·Medical Toxicology and Adverse Drug Experience·B AdinoffM Linnoila
Sep 25, 2012·Critical Care Clinics·Richard W CarlsonShivaramaiah Shashikumar
Sep 28, 2010·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Flora A Corfee
Sep 8, 2010·Drug and Alcohol Dependence·Robert S MansbachEdward M Sellers
Oct 1, 1994·Journal of Gerontological Nursing·S A MuddF C Blow
Nov 22, 2007·Progress in Neuro-psychopharmacology & Biological Psychiatry·Lorenzo LeggioRobert M Swift
Apr 17, 2007·Neuroscience Letters·Maria C Jockers-ScherüblRainer Hellweg
Sep 10, 2003·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Peter R Giancola, Ada C Mezzich
Mar 1, 2006·Internal Medicine Journal·A FoyC Sadler
Jun 21, 2013·Nursing in Critical Care·Joanne McPeakeJohn Kinsella
Apr 19, 2011·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Viktor Livshits, Joseph Rella
Nov 3, 2010·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Sara GrayMeldon Kahan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.