Development of pH-Responsive Biopolymeric Nanocapsule for Antibacterial Essential Oils

International Journal of Molecular Sciences
Sylvie SkalickovaPavel Horky

Abstract

It is generally believed that antibacterial essential oils have the potential to become one of the alternatives in preventing diarrheal diseases of monogastric animals. The disadvantage is their low efficiency per oral due to easy degradation during digestion in the stomach. This study compares the efficacy of chitosan, alginate-chitosan, guar gum-chitosan, xanthan gum-chitosan and pectin-chitosan nanocapsules to the synthesis of pH-responsive biopolymeric nanocapsule for Thymus vulgaris, Rosmarinus officinalis and Syzygium aromaticum essential oils. Using spectrophotometric approach and gas chromatography, release kinetics were determined in pH 3, 5.6 and 7.4. The growth rates of S. aureus and E. coli, as well as minimal inhibition concentration of essential oils were studied. The average encapsulation efficiency was 60%, and the loading efficiency was 70%. The size of the nanocapsules ranged from 100 nm to 500 nm. Results showed that chitosan-guar gum and chitosan-pectin nanocapsules released 30% of essential oils (EOs) at pH 3 and 80% at pH 7.4 during 3 h. Similar release kinetics were confirmed for thymol, eugenol and α-pinene. Minimal inhibition concentrations of Thymus vulgaris and Syzygium aromaticum essential oils range...Continue Reading

References

Feb 13, 2013·Carbohydrate Polymers·Vania Blasques BuenoDenise Freitas Siqueira Petri
Jun 6, 2014·The Veterinary Record·N De BriyneS P Borriello
Dec 22, 2014·Antonie van Leeuwenhoek·Simel Bağder ElmaciFiliz Özçelik
Mar 12, 2015·BioMed Research International·Jefferson Muniz de LimaLúcio Roberto Castellano
Apr 4, 2015·International Journal of Pharmaceutical Investigation·Nilesh KulkarniJitendra Naik
May 28, 2015·International Journal of Biological Macromolecules·Rongrui YouYanrui Dong
Jan 15, 2016·Journal of Drug Targeting·Lin ZhangAili Zhao
Mar 23, 2017·Carbohydrate Polymers·Arno VerleeChristian V Stevens
May 21, 2017·International Journal of Biological Macromolecules·M Sotelo-BoyásY Gómez Y Gómez
Jan 3, 2018·Nanomaterials·Sylvie SkalickovaRene Kizek
Aug 15, 2018·Journal of Drug Targeting·Sweet NaskarSuraj Sharma
Sep 5, 2018·Carbohydrate Polymers·Mina VolićBranko Bugarski
Mar 30, 2019·Biotechnology Journal·Jens Nielsen
Jun 16, 2019·Animals : an Open Access Journal From MDPI·Pavel HorkyJiri Skladanka
Sep 11, 2019·Materials Science & Engineering. C, Materials for Biological Applications·Fabiola Galbiatti de CarvalhoÂngelo Marcio Leite Denadai

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