PMID: 12756978May 22, 2003Paper

Development of pro- and antisaccades in children with attention-deficit hyperactivity disorder (ADHD) and healthy controls

Psychophysiology
C H KleinA Brandenbusch

Abstract

To date, the investigation of the antisaccade task, a simple test of "executive functions," in children with ADHD has yielded inconsistent results. The present study aimed at contributing to this issue by (a) the investigation of a large sample of carefully diagnosed ADHD patients aged 7-15 years, and (b) the analyses of differential age effects in patients and controls. Healthy control children were pairwise matched with patients (N = 46; age = 136 +/- 24 months) for age and gender, and did not significantly differ in IQ. Horizontal pro- and antisaccades were elicited under the 200-ms gap and overlap conditions (blocks of 100 trials each). Overall, patients exhibited (a) augmented pro- and antisaccadic reaction times, (b) augmented error rates (antitasks), (c) augmented proportions of early responses (all conditions), and (d) reduced proportions of express saccades under the prosaccadic gap condition. The greater decline in anti- as compared to pro-SRT with increasing age that characterized controls was missing in patients. Confirming Barkley's (1997) neuropsychological theory of ADHD, these results altogether point to alterations in "executive functions" in ADHD patients that are presumably supported by frontal lobe structure...Continue Reading

References

Jan 1, 1976·Archives of General Psychiatry·C ShagassM Amadeo
Oct 1, 1992·Brain : a Journal of Neurology·D BraunJ Schulte-Mönting
Jan 1, 1991·Journal of Child Neurology·K M HeilmanS E Nadeau
Apr 6, 1991·British Dental Journal·J Pinder
Jun 1, 1991·Brain : a Journal of Neurology·C Pierrot-DeseillignyY Agid
Nov 15, 1990·The New England Journal of Medicine·A J ZametkinR M Cohen
Jan 1, 1990·Journal of Psychiatric Research·J FukushimaI Yamashita
Jul 1, 1990·Journal of the American Academy of Child and Adolescent Psychiatry·D V LogeW W Beatty
Dec 1, 1988·Journal of Abnormal Child Psychology·J van der Meere, J Sergeant
May 1, 1988·Journal of the American Academy of Child and Adolescent Psychiatry·B B LaheyA Lorys-Vernon
Jan 1, 1986·European Archives of Psychiatry and Neurological Sciences·L MayfrankB Fischer
Jan 1, 1986·Child Psychiatry and Human Development·G J CheluneT O Dickey
Sep 1, 1986·Journal of Abnormal Child Psychology·S DraegerA Sanson
Aug 1, 1967·Journal of the Optical Society of America·M G Saslow
Sep 1, 1980·Comprehensive Psychiatry·J A Mattes
Jan 31, 1995·Proceedings of the National Academy of Sciences of the United States of America·G A O'DriscollP S Holzman
Jan 1, 1994·Experimental Brain Research·S RivaudC Pierrot-Deseilligny
Dec 1, 1994·The American Journal of Psychiatry·F X CastellanosJ L Rapoport
Jul 1, 1994·Journal of the American Academy of Child and Adolescent Psychiatry·R G RossA Radant
Jan 1, 1993·Experimental Brain Research·J CurrieV Malone
May 1, 1993·Archives of General Psychiatry·A J ZametkinR M Cohen
Dec 1, 1996·Perceptual and Motor Skills·S Hiraku, H Sakuma
Jan 1, 1997·Experimental Brain Research·J Goldring, B Fischer
Jan 1, 1997·The Journal of Nervous and Mental Disease·K K DowneyB Giordani
Dec 9, 1997·Neurobiology of Aging·A OlincyR Freedman
Dec 2, 2000·Biological Psychology·C H KleinA Schweickhardt

❮ Previous
Next ❯

Citations

Jul 2, 2005·Experimental Brain Research·Christoph Klein, Burkhart Fischer
May 31, 2006·Experimental Brain Research·Sandra JazbecMonique Ernst
Mar 8, 2011·Experimental Brain Research·Christoph KleinMonica Biscaldi
Sep 21, 2011·Experimental Brain Research·Eleanor J Dommett, Claire L Rostron
Oct 8, 2008·Development and Psychopathology·Kirsten O'HearnBeatriz Luna
Apr 18, 2008·Cognitive Neuropsychology·S Van der StigchelJ Theeuwes
Nov 9, 2010·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Laurie CarrJoel T Nigg
Jan 19, 2010·Journal of Psychopharmacology·Sven C MuellerMonique Ernst
Dec 20, 2011·BMC Pediatrics·Johanna GoepelIsabella Paul-Jordanov
Apr 3, 2014·Research in Developmental Disabilities·Maria Pia BucciChristophe-Loic Gerard
Aug 15, 2009·Cognitive, Affective & Behavioral Neuroscience·Matthias J WieserAndreas Mühlberger
May 26, 2009·Journal of the American Academy of Child and Adolescent Psychiatry·E Mark MahoneMartha B Denckla
Feb 25, 2009·Journal of the American Academy of Child and Adolescent Psychiatry·Irene M LoeBeatriz Luna
Nov 26, 2008·Brain and Cognition·S B Hutton
Oct 7, 2008·Brain and Cognition·Nanda N J RommelseJoseph A Sergeant
Jan 25, 2008·Medical Hypotheses·Paul G Overton
Oct 11, 2015·Brain Research·Louise R BraceEleanor J Dommett
Oct 16, 2015·Psychiatry Research·Nicolette F SchwarzJennifer E McDowell
Feb 14, 2007·Alcoholism, Clinical and Experimental Research·Courtney R GreenJames N Reynolds
Apr 22, 2008·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Kate Dimond FitzgeraldStephan F Taylor
Jul 22, 2014·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Cameron B JeterAnne B Sereno
Oct 1, 2014·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Mark H JohnsonTony Charman
Oct 7, 2011·Developmental Cognitive Neuroscience·Monique ErnstKyle Frantz
Dec 24, 2008·Brain Research·Elizabeth L IrvingMartin J Steinbach
Aug 18, 2004·Biological Psychology·Ulrich EttingerPhilip J Corr
Jun 30, 2006·Biological Psychiatry·Christoph KleinMartin Peper
May 23, 2015·Attention Deficit and Hyperactivity Disorders·Yun-Jeong LeeHo-Wan Kwak
Jun 14, 2005·Biological Psychiatry·Gillian A O'DriscollVirginia I Douglas
Feb 25, 2010·Experimental Psychology·Stefan Van der Stigchel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.