Development of resin adsorbents for blood purification at Nankai University in China

Artificial Cells, Blood Substitutes, and Immobilization Biotechnology
Yong-Jian Wang, Yao-Ting Yu

Abstract

Various types of porous resin adsorbents based on polystyrene, agarose, and cellulose as matrixes coupling with DNA, amino acids and other biological active molecules as ligands were extensively studied in China. Molecular recognition between the ligand and pathogenic molecule was investigated. Several commercialized products are now widely used in hospitals all over China. Whole blood hemoperfusion is used to treat patients suffering from autoimmune diseases, uremia acute intoxication, and hyperbilirubinemia. Clinical performances of hundreds and thousands of patients treated by whole blood sorption therapy show that the therapy is safe, efficient, and cost-effective.

References

Dec 1, 1969·Canadian Journal of Physiology and Pharmacology·T M Chang
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Sep 29, 2000·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·C FuC Chen
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Jun 25, 2005·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·Li YangYao-Ting Yu

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Citations

Nov 16, 2013·Artificial Cells, Nanomedicine, and Biotechnology·Vladimir G Nikolaev, Vitaliy A Samsonov

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