PMID: 2499547DOI: 10.1128/iai.57.7.2246-2248.1989Jul 1, 1989Paper
Development of resistance to Trypanosoma cruzi in mice depends on a viable population of L3T4+ (CD4+) T lymphocytes.
Infection and Immunity
F G Araujo
Abstract
Mice injected with monoclonal antibody to the L3T4+ (CD4+) cell membrane surface glycoprotein of T lymphocytes and immunized with antigens of Trypanosoma cruzi had reduced antibody and cell-mediated immune responses to the organism. Mortality in these mice was 100% following challenge with 1.5 x 10(5) trypanosomes, whereas controls had a 50% survival rate, indicating that T-cell activation and viable L3T4+ (CD4+) T lymphocytes are essential for the development of resistance.
References
Nov 1, 1979·Nature·M T Scott, D Snary
Jul 1, 1987·European Journal of Immunology·M Hontebeyrie-JoskowiczH Eisen
Sep 1, 1988·Immunology Today·K Bottomly
Jan 1, 1988·Transactions of the Royal Society of Tropical Medicine and Hygiene·A Ben Younès-ChennoufiM Hontebeyrie-Joskowicz
Jul 1, 1986·Infection and Immunity·F G Araujo
Dec 1, 1985·Experimental Parasitology·N W AndrewsW Colli
Oct 1, 1973·Experimental Parasitology·E L Roberson, W L Hanson
Jan 1, 1971·Transactions of the Royal Society of Tropical Medicine and Hygiene·G A SchmunisJ F Janovsky
Jan 1, 1983·Immunological Reviews·D P DialynasJ Kappler
May 1, 1984·The American Journal of Tropical Medicine and Hygiene·F G Araujo, D Guptill
Jul 1, 1985·Parasitology Today·F Kierszenbaum
Jul 1, 1985·Parasitology Today·L Hudson
❮ Previous
Next ❯
Citations
Jul 4, 1998·Parasite Immunology·S Kumar, R L Tarleton
Dec 22, 1999·Infection and Immunity·D F HoftS T Roodman
May 19, 2000·Infection and Immunity·A E Millar, S J Kahn
Aug 17, 2002·Infection and Immunity·Anita R SchnappDaniel F Hoft
Jul 20, 2007·Scandinavian Journal of Immunology·C R F MarinhoJ M Alvarez
Jul 20, 2012·Clinical & Developmental Immunology·Denise Bertulucci Rocha RodriguesVirmondes Rodrigues
Mar 26, 1992·Nature·R L TarletonM Postan
Sep 1, 1992·Revista Do Instituto De Medicina Tropical De São Paulo·S GeaE Vottero-Cima
May 1, 1993·Scandinavian Journal of Immunology·M E RottenbergA Orn
Feb 1, 1995·Scandinavian Journal of Immunology·M E RottenbergA Orn
Feb 14, 2002·Scandinavian Journal of Immunology·F CardilloJ Mengel
Aug 1, 1992·Scandinavian Journal of Immunology·M E RottenbergA Orn
Nov 5, 2002·Annual Review of Immunology·Phillip Wong, Eric G Pamer
Aug 9, 2003·DNA and Cell Biology·David A Brake
Aug 12, 2014·Mediators of Inflammation·José M ÁlvarezMaria Regina D'Império Lima
Dec 19, 2001·Infection and Immunity·Malcolm S DuthieStuart J Kahn
Dec 3, 1999·Parasite Immunology·S F NevesR Correa-Oliveira
Aug 28, 2009·Journal of Pineal Research·Fabricia H SantelloJosé C do Prado
Jan 27, 1999·Experimental Parasitology·C N PaivaC R Gattass
Nov 1, 1996·International Journal for Parasitology·D LaderachS Gea
Dec 1, 1995·Immunology Letters·A TaibiA Ouaissi
Sep 1, 1991·Infection and Immunity·F G Araujo, B Morein
May 1, 1991·Infection and Immunity·F G Araujo
Apr 1, 1998·Clinical and Diagnostic Laboratory Immunology·L VerinaudI J Camargo
Dec 1, 1993·Infection and Immunity·M E RottenbergA Orn
May 1, 1994·Infection and Immunity·R L TarletonM Postan
Jul 1, 1996·Infection and Immunity·C A HunterF Araujo
Sep 1, 1996·Infection and Immunity·D F HoftD Shaffer
Aug 1, 1993·Infection and Immunity·S P NickellM So
Jan 1, 1995·Infection and Immunity·R A WrightsmanJ E Manning
Aug 1, 1991·Experimental Parasitology·M E RottenbergE L Segura
Aug 8, 2009·Microbes and Infection·Cláudio R F MarinhoJosé M Alvarez
Mar 1, 1997·Infection and Immunity·S FroschB Fleischer
❮ Previous
Next ❯
Related Concepts
Related Feeds
Related Papers
Infection and Immunity
F G Araujo
Scandinavian Journal of Immunology
M E RottenbergA Orn
The Journal of Rheumatology
N G LevittP H Wooley
Microbiology and Immunology
H NagasawaK Himeno