PMID: 9421752Jan 1, 1997Paper

Development of self-anchoring bone implants. I. Processing and material characterization

Journal of Biomedical Materials Research
A AbusafiehS Kalidindi

Abstract

We recently designed and produced a family of new swelling-type materials that are potentially capable of self-fixation in bone. These materials are designed to absorb body fluids and swell by small amounts, which will allow the implants made from these materials to achieve self-fixation by an expansion-fit mechanism. The developed material system is essentially a crosslinked random copolymer based on poly (methyl methacrylate-acrylic acid). For potential structural (load-bearing) bioimplant applications, we reinforced this copolymer with AS-4 carbon and Kevlar 49 fibers. The details of processing these materials and the steps involved in optimizing their microstructures are presented in this article. A set of mechanical tests were performed on these materials in both dry and swollen conditions to measure their moduli and yield strengths. In the dry state, the copolymers were found to exhibit Young's moduli in the range of 3 to 4 GPa and yield strengths in the range of 70 to 85 MPa. The reinforced composites exhibited moduli in the range of 15 to 65 GPa and yield strengths in the range of 125 to 500 MPa. Upon controlling the volumetric swelling in these materials to be less than about 10%, the loss in mechanical properties was ...Continue Reading

References

Nov 1, 1978·Journal of Biomedical Materials Research·A R GreenbergA Miller
Jan 1, 1975·Journal of Biomechanics·D T Reilly, A H Burstein
Jan 1, 1992·Journal of Biomedical Materials Research·W J DhertP M Rozing
Jan 1, 1973·Journal of Biomedical Materials Research·E Sclippa, K Piekarski
Mar 1, 1972·Journal of Biomechanics·A Chamay, P Tschantz
Mar 1, 2013·Journal of Biomechanical Engineering·Michael S SacksVictor Barocas

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Citations

Mar 10, 2001·Journal of Biomedical Materials Research·Y H NienS Siegler
Aug 11, 2000·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G M GualtieriS R Kalidindi
Nov 24, 2004·Colloids and Surfaces. B, Biointerfaces·Kalpana S Katti

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