Development of stable curcumin nanoemulsions: effects of emulsifier type and surfactant-to-oil ratios

Journal of Food Science and Technology
Peihua MaFang Yuan

Abstract

Curcumin, a natural polyphenolic compound, offers a wide range of pharmacological benefits such as antioxidant, anti-inflammatory and anti-cancer. The oil-in-water nanoemulsions containing curcumin were obtained by high pressure homogenization and effects of various emulsifiers (Tween-80, lecithin, whey protein isolate and acacia) and different surfactant-to-oil ratios (SOR) on physicochemical characteristics, physical stability and storage stability of curcumin loaded nanoemulsions were evaluated in this study. The result showed that smaller particle size, better physical and storage stabilities and higher curcumin content were found in curcumin loaded nanoemulsions stabilized with Tween-80 and lecithin. Compared with nanoemulsions prepared with lecithin, nanoemulsions fabricated with Tween-80 exhibited better uniformity and distribution as demonstrated by microscopic observations. It was found that SOR was positively correlated with particle size but negatively correlated with curcumin content in the emulsion droplets. Neither the emulsifier nor SOR values were found to have significant effects on zeta-potentials of the droplets. This result implied that curcumin loaded nanoemulsions prepared with Tween-80 and higher SOR valu...Continue Reading

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Citations

May 11, 2021·Journal of the Science of Food and Agriculture·Jose Antonio Vellido-PerezAntonio Martinez-Ferez

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