Development of systemic lupus erythematosus in an elderly male hemodialysis patient with pleuritis

CEN Case Reports
Maki TsukamotoMasaomi Nangaku

Abstract

This report describes a 70-year-old man who developed systemic lupus erythematosus (SLE) during treatment with maintenance hemodialysis. At initiation of maintenance dialysis, the etiology of end-stage renal disease (ESRD) was diabetic nephropathy and no clinical symptom or laboratory data suggested SLE. Fever, pleural effusion that did not respond to ultrafiltration, and immunological findings such as low complement and elevated anti-double-strand DNA antibody level appeared 4 years after maintenance dialysis initiation. Immunosuppressive therapy with corticosteroids improved these abnormalities remarkably. This case underscores the necessity of considering SLE in the differential diagnosis of pleural effusion with male ESRD patients, even if another etiology of ESRD exists.

References

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Mar 3, 2012·The Journal of Rheumatology·Tze Chin TanMichelle A Petri

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Citations

Jul 18, 2017·Anatomy & Cell Biology·Satheesha B NayakAbhinitha Padavinangadi

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