Development of the acoustic startle response in rats and its change after early acoustic trauma

Behavioural Brain Research
N RybalkoJosef Syka

Abstract

Even brief acoustic trauma during the critical period of development that results in no permanent hearing threshold shift may lead to altered auditory processing in adulthood. By monitoring the acoustic startle response (ASR), we examined the development of auditory function in control rats and in rats exposed to intense noise at the 14th postnatal day (P14). First ASRs appeared on P10-P11 to intense low-frequency tones. By P14, the range of sound intensities and frequencies eliciting ASRs extended considerably, the ASR reactivity being similar at all frequencies (4-32 kHz). During the subsequent two weeks, ASR amplitudes to low-frequency stimuli (4-8 kHz) increased, whereas the ASRs to high-frequency tones were maintained (16 kHz) or even decreased (32 kHz). Compared to controls, noise exposure on P14 (125 dB SPL for 8, 12, or 25 min) produced transient hyper-reactivity to startle stimuli, manifested by a decrease of ASR thresholds and an increase of ASR amplitudes. ASR enhancement occurred regardless of permanent hearing loss and was more pronounced at high frequencies. The hyper-reactivity of ASRs declined by P30; the ASR amplitudes in adult exposed rats were lower than in controls. The histological control did not reveal lo...Continue Reading

References

Nov 1, 1976·The Annals of Otology, Rhinology, and Laryngology·B A Bohne
Mar 1, 1987·Journal of Comparative Psychology·P K PilzD Menne
Jan 1, 1983·Psychopharmacology·C KelloggR K Miller
Sep 15, 1984·Toxicology and Applied Pharmacology·K M Crofton, L W Reiter
Feb 1, 1980·Journal of Comparative and Physiological Psychology·A Shnerson, J F Willott
Dec 1, 1993·The Journal of the Acoustical Society of America·E Zimmermann
Jun 8, 2000·Annals of the New York Academy of Sciences·R Pujol, J L Puel
Aug 15, 2000·Neuroscience and Biobehavioral Reviews·K C Ross, J R Coleman
Aug 30, 2000·Hearing Research·R J SalviD Ding
May 4, 2001·Hearing Research·N Rybalko, J Syka
Oct 17, 2002·Journal of the Association for Research in Otolaryngology : JARO·Yong WangM Charles Liberman
Oct 27, 2004·Hearing Research·Agneta Viberg, Barbara Canlon
Nov 13, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Sharon G Kujawa, M Charles Liberman
Jul 6, 2010·The European Journal of Neuroscience·Zbynek BuresJosef Syka
Nov 26, 2010·Neuroscience and Biobehavioral Reviews·Arnaud Jean Noreña
May 25, 2011·Journal of the Association for Research in Otolaryngology : JARO·Jonathon P Whitton, Daniel B Polley
Jun 21, 2011·Journal of the Association for Research in Otolaryngology : JARO·Harrison W LinM Charles Liberman
Feb 27, 2013·Journal of the Association for Research in Otolaryngology : JARO·G ChenJ A Kaltenbach
Nov 8, 2013·Journal of Neurophysiology·Ann E Hickox, M Charles Liberman
Nov 12, 2014·Frontiers in Neurology·Benjamin D AuerbachRichard J Salvi

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Citations

Mar 10, 2015·Physiology & Behavior·Daniel ŠutaJosef Syka
Jan 15, 2017·Hearing Research·M Charles Liberman, Sharon G Kujawa
Dec 5, 2019·The Journal of the Acoustical Society of America·Celia D EscabiEdward Lobarinas
Sep 10, 2019·Frontiers in Aging Neuroscience·Zbyněk BurešJosef Syka
Aug 20, 2021·Scientific Reports·Roman MakarovRoustem Khazipov

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