PMID: 3766993Jan 1, 1986Paper

Development of the auditory hair cell surface in human fetuses. A scanning electron microscopy study

Anatomy and Embryology
M Lavigne-Rebillard, R Pujol

Abstract

Thirteen human fetal cochleas were investigated by scanning electron microscopy. Our observations concentrated on the hair cell surface. Ciliogenesis appeared to start during the 11th week of gestation on the inner hair cells (IHCs) and one week later on the outer hair cells (OHCs). The earliest stages of stereociliary development were similar on both types of cell and were characterized by the presence of round bundles of cilia arising from the surrounding microvilli. A three-dimensional V-shaped arrangement suddenly appeared, accompanied by the disappearance of short cilia on the internal side. Between the 20th and the 22nd weeks of gestation, both types of hair cell had an adult stereociliary pattern, i.e. a rectilinear arrangement on IHCs and W-shaped on OHCs. However, there were signs of immaturity, such as a disarray of OHCs and the presence of the kinocilium, suggesting that the surface of the auditory hair cells achieves its maturation during the last trimester of pregnancy.

References

Nov 1, 1979·The Annals of Otology, Rhinology, and Laryngology·K TanakaY Terayama
May 1, 1978·Acta Oto-laryngologica·I Kawabata, Y Nomura
Jan 1, 1985·Acta Oto-laryngologica. Supplementum·R Pujol, M Lavigne-Rebillard
Sep 1, 1985·American Journal of Otolaryngology·C J Dechesne, A Sans
Nov 1, 1984·Brain Research·D A Cotanche, K K Sulik
Jan 1, 1984·Archives of Oto-rhino-laryngology·A Sobin, M Anniko
Jan 1, 1983·Anatomy and Embryology·M Anniko
May 1, 1983·Acta Oto-laryngologica·J M Sánchez FernándezJ A Macias
Aug 1, 1980·Archivum Histologicum Japonicum = Nihon Soshikigaku Kiroku·Y Igarashi

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Citations

May 1, 1988·Acta Oto-laryngologica·M Lavigne-Rebillard, R Pujol
Jan 1, 1987·Anatomy and Embryology·M LenoirR Pujol
Oct 16, 2002·Cell Motility and the Cytoskeleton·Nicolas Daudet, Marie-Christine Lebart
Jan 1, 1992·Acta Oto-laryngologica·R Pujol, M Lavigne-Rebillard
Jan 1, 1993·Cell Motility and the Cytoskeleton·R RomandA Hafidi
Jul 24, 2001·The Annals of Otology, Rhinology, and Laryngology·J K Moore, F H Linthicum
Sep 11, 2007·International Journal of Audiology·Jean K Moore, Fred H Linthicum
Oct 10, 2012·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Helge Rask-AndersenRudolf Glueckert
Jul 13, 2016·Autism Research : Official Journal of the International Society for Autism Research·Loisa BennettoAnne E Luebke
Aug 14, 2019·Journal of the Association for Research in Otolaryngology : JARO·Sebastiaan W F MeenderinkCarolina Abdala
Jun 1, 1990·Journal of Electron Microscopy Technique·M Lavigne-Rebillard, R Pujol
Sep 1, 1988·Acta Oto-laryngologica·T KikuchiT Takasaka
Jan 1, 1987·Acta Oto-laryngologica. Supplementum·M Lavigne-Rebillard, R Pujol
Apr 15, 2008·Human Molecular Genetics·Anna RajabMehul T Dattani
Mar 21, 2019·Frontiers in Cell and Developmental Biology·Cristiana MatteiMirella Dottori
Feb 26, 2014·Archives of Sexual Behavior·Sarah M BurkeJulie Bakker
Jan 12, 2010·The Journal of the Acoustical Society of America·Carolina Abdala, Sumitrajit Dhar
Jun 1, 1995·International Journal of Pediatric Otorhinolaryngology·R Pujol, M Lavigne-Rebillard
Oct 1, 1996·Hearing Research·S Zhou, J O Pickles
May 20, 1996·Brain Research·A Zine, R Romand
May 12, 2021·Ear and Hearing·Srikanta K MishraHansapani Rodrigo
Dec 8, 1991·The Journal of Comparative Neurology·Y RaphaelR Pujol
Apr 22, 1992·The Journal of Comparative Neurology·M Vater, M Lenoir
Aug 4, 2021·Human Genetics·Daniel R RomanoRick F Nelson
Apr 30, 1993·Science·P P LefebvreT R Van de Water

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