Development of the Berlin Symptom Checklist Ovary (BSCL-O) for the measurement of quality of life of patients with primary and recurrent ovarian cancer: results of a phase I and II study

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Dominique KoensgenNord-Ostdeutschen Gesellschaft für Gynäkologische Onkologie (NOGGO) working group "Quality of life"

Abstract

Quality of life (Qol) represents a relevant end point in the clinical management of advanced ovarian cancer (AOC). However, there exist only a few specific instruments which have been designed for patients with ovarian cancer. The aim of this study was to develop a systematic checklist (Berlin Symptom Checklist Ovary (BSCL-O)) as an instrument of Qol for patients with AOC and to discriminate between the frequency and the importance of symptoms. The main symptoms were identified in a phase I study via free interviews of five patients with ovarian cancer (OC) as well as five medical doctors, family dependent, and care workers. In the phase II study, the capability of BSCL-O was evaluated by questionnaire-guided interviews of 200 patients with primary OC, recurrent OC, metastasized breast cancer, and benign ovarian tumors. In phase I, 36 main symptoms were identified. In phase II, 7,200 answers from 98.5% of all patients were evaluable. Of the 36 symptoms of the BSCL-O, 23 revealed clinical relevance. There was a correlation of frequency and importance of symptoms (p < 0.05). The symptoms of the BSCL-O were deemed twice as strenuous in patients with recurrent OC. The BSCL-O can measure Qol of patients with OC. The BSCL-O is being ...Continue Reading

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Citations

Dec 4, 2012·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Beata Penar-ZadarkoKrzysztof Urbanski
Sep 14, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Koji MatsuoNeil B Rosenshein

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