Development of the hip in diastrophic dysplasia

The Journal of Bone and Joint Surgery. British Volume
P VaaraS Ryöppy

Abstract

We examined 50 patients with diastrophic dysplasia both clinically and radiologically. Two legally aborted fetuses were dissected. The mean age of the patients was 16.2 years (newborn to 38) and the mean follow-up was 11.4 years (3 months to 34 years). The fetal hips and MRI of newborn infants showed congruity and no significant joint deformity. Flexion contracture of the hip became evident later in 93% and was progressive. The radiological appearance of the proximal femoral ossific nuclei was delayed and in 17% of males and 28% of females the ossific nuclei had not appeared by the age of 12 years. Radiological measurements differed considerably from reference values and were related to the rapid and progressive restriction of rotational movement and the increase in flexion contracture. The typical findings were flattening and inferomedial bulking of the femoral head and a double-hump deformation. The changes in the hip led to secondary osteoarthritis before early middle age. We describe the clinical and radiological measurements which define the early degeneration of the joint.

Citations

Apr 18, 2015·The Journal of Arthroplasty·Daniel GuentherCarl Haasper
Nov 29, 2014·Orthopaedic Surgery·Ali Al KaissiFranz Grill
Aug 22, 2015·Journal of Pediatric Orthopedics·Ilhan A BayhanWilliam G Mackenzie
Jun 10, 2000·Scandinavian Journal of Public Health·P VaaraS Ryöppy
Feb 22, 2002·Journal of Pediatric Orthopedics·Ville RemesJari Peltonen
Oct 29, 2003·Journal of Pediatric Orthopedics·Jari PeltonenPekka Tervahartiala
May 27, 2010·Journal of Pediatric Orthopedics·Dennis S WeinerSteven Kopits
Jul 21, 2006·Journal of Neurosurgery. Spine·Robert A Beatty
Aug 12, 2005·Journal of Pediatric Orthopedics. Part B·Marie-Eve LeBel, Roger Gallien
Feb 13, 2004·The Journal of Bone and Joint Surgery. American Volume·John B ChiavettaMiguel E Cabanela
Apr 3, 2009·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·B D SheridanF P Monsell
Mar 15, 2003·The Journal of Bone and Joint Surgery. American Volume·Ilkka HeleniusTimo Paavilainen
Nov 25, 2003·The Journal of Bone and Joint Surgery. American Volume·Ilkka HeleniusTimo Paavilainen

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