PMID: 3764292Jun 1, 1986Paper

Development of the indications for celioscopic biopsy of the ovaries. 408 cases over a 20-year period

Revue française de gynécologie et d'obstétrique
M Mintz, J de Brux

Abstract

Indications for per-laparoscopic ovarian biopsy has decreased significantly during the last two decades, thanks to the progress in hormone assays and new drugs. Despite this, there is still place for ovarian biopsy in the following circumstances: in the rare cases of amenorrhea with high levels of FSH and LH, the value of biopsy is important for distinguishing between early menopause and gonadotropin-resistant ovaries; it allows the clinician to refrain from or to increase his therapy; in the few cases of Stein-Leventhal or borderline syndromes, there is a place for laparoscopic biopsy after failure of hormonal treatment, if only to avoid post-laparotomy adhesions. The greatest value is in infertility, because of the frequency of ovarian factors and the success rate of laparoscopy coupled with ovarian biopsy.

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